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HLA-B 抗体

(Major Histocompatibility Complex, Class I, B (HLA-B))

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008].

recommended

HLA-B 抗体 (AA 26-309) (ABIN7440755)

HLA-B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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recommended

HLA-B 抗体 (AA 241-362) (ABIN5542339)

HLA-B 适用: 人 WB, ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 2A11G7 unconjugated

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recommended

HLA-B 抗体 (N-Term) (ABIN1944779)

HLA-B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB47637 unconjugated

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HLA-B 抗体 by Grade

Find HLA-B 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

HLA-B 抗体 by 适用

Find HLA-B 抗体 for a variety of species such as anti-Human HLA-B, anti-Mouse HLA-B, anti-Rat HLA-B. The species listed below are among those available. Click on a link to go to the corresponding products.

HLA-B 抗体 by 应用范围

Find HLA-B 抗体 validated for a specific application such as WB, ELISA, FACS, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

HLA-B 抗体 by 抗体来源

Find HLA-B 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

HLA-B 抗体 by 抗原表位

Find HLA-B 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

HLA-B 抗体 by 克隆形成能力

Find available monoclonal or polyclonal HLA-B 抗体. Click on a link to go to the corresponding products.

HLA-B 抗体 by 克隆

Find HLA-B 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

HLA-B 抗体 by 标记

Find HLA-B 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular HLA-B 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-HLA-B 抗体 (AA 26-309)

Reactivity Human

Application WB, IHC, IP, ICC

Validations

Cat. No. ABIN7440755

Quantity 100 μL

Datasheet Datasheet

anti-HLA-B 抗体 (AA 241-362)

Reactivity Human

Application WB, ELISA, FACS, IHC, ICC

Validations

Cat. No. ABIN5542339

Quantity 100 μL

Datasheet Datasheet

anti-HLA-B 抗体 (N-Term)

Reactivity Human

Application WB, IHC (p)

Validations

Cat. No. ABIN1944779

Quantity 400 μL

Datasheet Datasheet

anti-HLA-B 抗体 (AA 1-100)

Reactivity Human

Application WB, IHC, IF

Validations

Cat. No. ABIN1513015

Quantity 100 μg

Datasheet Datasheet

anti-HLA-B 抗体

Reactivity Human, Mouse, Rat

Application WB, IHC

Validations

Cat. No. ABIN7256404

Quantity 200 μL

Datasheet Datasheet

anti-HLA-B 抗体 (AA 25-308)

Reactivity Human

Application WB, ELISA, IHC, IF

Validations

Cat. No. ABIN7155621

Quantity 100 μg

Datasheet Datasheet

anti-HLA-B 抗体 (AA 1-362)

Reactivity Human

Application WB

Validations

Cat. No. ABIN516466

Quantity 50 μg

Datasheet Datasheet

anti-HLA-B 抗体 (AA 209-295)

Reactivity Human

Application WB, ELISA

Validations

Cat. No. ABIN7193420

Quantity 100 μL

Datasheet Datasheet

anti-HLA-B 抗体 (AA 243-308)

Reactivity Human

Application WB, ELISA, IF

Validations

Cat. No. ABIN7155555

Quantity 100 μL

Datasheet Datasheet

anti-HLA-B 抗体 (AA 197-306)

Reactivity Human

Application WB, ELISA, IHC

Validations

Cat. No. ABIN7155563

Quantity 100 μg

Datasheet Datasheet

anti-HLA-B 抗体 (AA 25-308) (Biotin)

Reactivity Human

Application ELISA, IHC

Validations

Cat. No. ABIN7155622

Quantity 100 μg

Datasheet Datasheet

anti-HLA-B 抗体

Reactivity Human

Application WB, ELISA, IHC

Validations

Cat. No. ABIN7244867

Quantity 200 μL

Datasheet Datasheet

anti-HLA-B 抗体 (AA 132-143)

Reactivity Human

Application WB, ELISA, IHC

Validations

Cat. No. ABIN5539557

Quantity 100 μg

Datasheet Datasheet

anti-HLA-B 抗体 (Internal Region)

Reactivity Human

Application WB, ELISA, IHC

Validations

Cat. No. ABIN5539556

Quantity 100 μg

Datasheet Datasheet

anti-HLA-B 抗体 (N-Term)

Reactivity Human

Application WB, FACS, IHC (p)

Validations

Cat. No. ABIN652557

Quantity 400 μL

Datasheet Datasheet

Latest Publications for our HLA-B 抗体

Lorente, Infantes, Abia, Barnea, Beer, García, Lasala, Jiménez, Mir, Morreale, Admon, López et al.: "A viral, transporter associated with antigen processing (TAP)-independent, high affinity ligand with alternative interactions endogenously presented by the nonclassical human leukocyte antigen E ..." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 34895-903, (2012) (PubMed).

Lorente, García, López: "Allele-dependent processing pathways generate the endogenous human leukocyte antigen (HLA) class I peptide repertoire in transporters associated with antigen processing (TAP)-deficient cells." in: The Journal of biological chemistry, Vol. 286, Issue 44, pp. 38054-9, (2011) (PubMed).

Lorente, Infantes, Barnea, Beer, García, Lasala, Jiménez, Vilches, Lemonnier, Admon, López: "Multiple viral ligands naturally presented by different class I molecules in transporter antigen processing-deficient vaccinia virus-infected cells." in: Journal of virology, Vol. 86, Issue 1, pp. 527-41, (2011) (PubMed).

Lin, Tokunaga, Tanaka, Nakajima, Imanishi, Kashiwase, Bannai, Mizuno, Akaza, Tadokoro, Shibata, Juji: "Further molecular diversity in the HLA-B15 group." in: Tissue antigens, Vol. 47, Issue 4, pp. 265-74, (1996) (PubMed).

Hildebrand, Domena, Shen, Lau, Terasaki, Bunce, Marsh, Guttridge, Bias, Parham: "HLA-B15: a widespread and diverse family of HLA-B alleles." in: Tissue antigens, Vol. 43, Issue 4, pp. 209-18, (1994) (PubMed).

Little, Parham: "The HLA-Bw75 subtype of B15: molecular characterization and comparison with crossreacting antigens." in: Tissue antigens, Vol. 38, Issue 4, pp. 186-90, (1992) (PubMed).

Madrigal, Belich, Hildebrand, Benjamin, Little, Zemmour, Ennis, Ward, Petzl-Erler, du Toit: "Distinctive HLA-A,B antigens of black populations formed by interallelic conversion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 10, pp. 3411-5, (1992) (PubMed).

Watkins, McAdam, Liu, Strang, Milford, Levine, Garber, Dogon, Lord, Ghim: "New recombinant HLA-B alleles in a tribe of South American Amerindians indicate rapid evolution of MHC class I loci." in: Nature, Vol. 357, Issue 6376, pp. 329-33, (1992) (PubMed).

Aliases for HLA-B 抗体

major histocompatibility complex, class I, B (HLA-B) 抗体
major histocompatibility complex, class I, B (BOLA-B) 抗体
major histocompatibility complex, class I, B (MAMU-B18) 抗体
major histocompatibility complex, class I, B (DKFZP469N1225) 抗体
major histocompatibility complex nonclassical class Ib L homeolog (mhc1b.L) 抗体
AS 抗体
HLAB 抗体
mhc1b 抗体
SPDA1 抗体

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HLA-B 抗体 by Grade

HLA-B 抗体 by 适用

HLA-B 抗体 by 应用范围

HLA-B 抗体 by 抗体来源

HLA-B 抗体 by 抗原表位

HLA-B 抗体 by 克隆形成能力

HLA-B 抗体 by 克隆

HLA-B 抗体 by 标记

Popular HLA-B 抗体

Latest Publications for our HLA-B 抗体

Aliases for HLA-B 抗体

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