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HLA-A 蛋白

(Major Histocompatibility Complex, Class I, A (HLA-A))

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008].

recommended

HLA-A Protein (AA 24-365) (GST tag) (ABIN1306741)

HLA-A 宿主: 人宿主: 小麦胚 Recombinant WB, AP, AA, ELISA

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recommended

HLA-A Protein (AA 83-352) (His tag) (ABIN7412848)

HLA-A 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 90 % WB, SDS, Imm, PC

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recommended

HLA-A Protein (Fc Tag) (ABIN6964124)

HLA-A 宿主: 人宿主: HEK-293 Cells Recombinant

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HLA-A 蛋白 by Origin

Find HLA-A 蛋白 for a variety of species such as anti-Human HLA-A, anti-Rabbit HLA-A. The species listed below are among those available. Click on a link to go to the corresponding products.

HLA-A 蛋白 by Source

Here you will find HLA-A 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

HLA-A 蛋白 by 蛋白类型

Here you can find HLA-A 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

HLA-A 蛋白 by 应用范围

Find HLA-A 蛋白 validated for a specific application such as WB, Imm, PC, SDS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular HLA-A 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

HLA-A Protein (AA 24-365) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1306741

Quantity 10 μg

Datasheet Datasheet

HLA-A Protein (AA 83-352) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7412848

Quantity 100 μg

Datasheet Datasheet

HLA-A Protein (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN6964124

Quantity 100 μg

Datasheet Datasheet

HLA-A Protein (His tag)

Reactivity Rabbit

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7404614

Quantity 100 μg

Datasheet Datasheet

HLA-A 蛋白

Reactivity Human

Source

Validations

Cat. No. ABIN1065552

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our HLA-A 蛋白

Klöß, Chambron, Gardlowski, Arseniev, Koch, Esser, Glienke, Seitz, Köhl: "Increased sMICA and TGFβ1 levels in HNSCC patients impair NKG2D-dependent functionality of activated NK cells." in: Oncoimmunology, Vol. 4, Issue 11, pp. e1055993, (2015) (PubMed).

Aliases for HLA-A 蛋白

major histocompatibility complex, class I, A (HLA-A) 蛋白
HLAA 蛋白

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HLA-A 蛋白 by Origin

HLA-A 蛋白 by Source

HLA-A 蛋白 by 蛋白类型

HLA-A 蛋白 by 应用范围

Popular HLA-A 蛋白

Latest Publications for our HLA-A 蛋白

Aliases for HLA-A 蛋白

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