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Histone H2A Variant H2A.Z, Pht1 产品

(Histone H2A Variant H2A.Z, Pht1 (PHT1))

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Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Important for chromosomal structure and function, possibly including a role in controlling the fidelity of chromosomal segregation during mitosis. Plays an important role in maintaining a silenced chromatin state at centromeres and in the architecture of anaphase chromosomes. {ECO:0000269|PubMed:17947424, ECO:0000269|PubMed:19910462, ECO:0000269|PubMed:19915592}.

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Histone H2A Variant H2A.Z, Pht1 抗体

High quality antibodies with extensive validation data.

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Recommended Histone H2A Variant H2A.Z, Pht1 蛋白

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Latest Publications for our Histone H2A Variant H2A.Z, Pht1 Products

Tapia-Alveal, Lin, Yeoh, Jabado, OConnell: "H2A.Z-dependent regulation of cohesin dynamics on chromosome arms." in: Molecular and cellular biology, Vol. 34, Issue 11, pp. 2092-104, (2014) (PubMed).

Synonyms and alternative names related to Histone H2A Variant H2A.Z, Pht1

histone H2A variant H2A.Z, Pht1 (pht1)
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