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Histone H2A Variant 抗体

(Histone H2A Variant (HIS2AV))

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repressive state of homeotic genes of the animal throughout development. Required for histone H3 'Lys-9' methylation and histone H4 'Lys-12' acetylation, two modifications that are essential for heterochromatin formation. Also involved in DNA double strand break (DSB) repair. Essential for early development.

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Histone H2A Variant (HIS2AV) (Internal Region), (pSer137) 抗体 (ABIN129671)

HIS2AV 适用: Drosophila melanogaster ELISA, WB 宿主: 兔 Polyclonal unconjugated

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Popular Histone H2A Variant 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-Histone H2A Variant (HIS2AV) (Internal Region), (pSer137) 抗体

Reactivity Drosophila melanogaster

Application ELISA, WB

Validations

(27)
(10)

Cat. No. ABIN129671

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our Histone H2A Variant 抗体

Lin, Wang, Lin, Rastegari, Su, Chang, Liao, Chang, Pi, Yu, Chen, Lin, Lu, Su, Tzou, Chan, Hsu: "Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling." in: Nature communications, Vol. 11, Issue 1, pp. 3147, (2020) (PubMed).

Perlmutter, Bordenstein, Unckless, LePage, Metcalf, Hill, Martinez, Jiggins, Bordenstein: "The phage gene wmk is a candidate for male killing by a bacterial endosymbiont." in: PLoS pathogens, Vol. 15, Issue 9, pp. e1007936, (2020) (PubMed).

Grendler, Lowgren, Mills, Losick: "Wound-induced polyploidization is driven by Myc and supports tissue repair in the presence of DNA damage." in: Development (Cambridge, England), Vol. 146, Issue 15, (2020) (PubMed).

Tsakiri, Gumeni, Vougas, Pendin, Papassideri, Daga, Gorgoulis, Juhász, Scorrano, Trougakos: "Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy." in: Autophagy, Vol. 15, Issue 10, pp. 1757-1773, (2020) (PubMed).

Mlih, Khericha, Birdwell, West, Karpac: "A virus-acquired host cytokine controls systemic aging by antagonizing apoptosis." in: PLoS biology, Vol. 16, Issue 7, pp. e2005796, (2019) (PubMed).

Cosolo, Jaiswal, Csordás, Grass, Uhlirova, Classen: "JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress." in: eLife, Vol. 8, (2019) (PubMed).

Merigliano, Mascolo, La Torre, Saggio, Vernì: "Protective role of vitamin B6 (PLP) against DNA damage in Drosophila models of type 2 diabetes." in: Scientific reports, Vol. 8, Issue 1, pp. 11432, (2018) (PubMed).

Harumoto, Lemaitre: "Male-killing toxin in a bacterial symbiont of Drosophila." in: Nature, Vol. 557, Issue 7704, pp. 252-255, (2018) (PubMed).

McCarthy, Deiulio, Martin, Upadhyay, Rangan: "Tip60 complex promotes expression of a differentiation factor to regulate germline differentiation in female Drosophila." in: Molecular biology of the cell, Vol. 29, Issue 24, pp. 2933-2945, (2018) (PubMed).

Caridi, DAgostino, Ryu, Zapotoczny, Delabaere, Li, Khodaverdian, Amaral, Lin, Rau, Chiolo: "Nuclear F-actin and myosins drive relocalization of heterochromatic breaks." in: Nature, Vol. 559, Issue 7712, pp. 54-60, (2018) (PubMed).

Aliases for Histone H2A Variant 抗体

Histone H2A variant (His2Av) 抗体
5499 抗体
CG5499 抗体
Dmel\\CG5499 抗体
gamma-H2Av 抗体
gamma-HIS2AV 抗体
gamma-His2Av 抗体
gammaH2Av 抗体
H2A 抗体
H2A.F/Z 抗体
H2a.V 抗体
H2A.X 抗体
H2A.Z 抗体
H2AV 抗体
H2Av 抗体
H2av 抗体
H2AvD 抗体
H2avD 抗体
h2AvD 抗体
H2AV_DROM 抗体
H2AX 抗体
H2AZ 抗体
HIS 抗体
His 抗体
his 抗体
His2 抗体
HIS2AV 抗体
His2AV 抗体
HIS2AVD 抗体
His2AvD 抗体
HisH2Av 抗体
Hist 抗体
Hist2av 抗体
l(3)05146 抗体
l(3)97Dd 抗体
l(3)810 抗体
l(3)L1602 抗体

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