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HIP1 产品

(Huntingtin Interacting Protein 1 (HIP1))

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The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

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Featured HIP1 Categories

HIP1 抗体

High quality antibodies with extensive validation data.

HIP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

HIP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HIP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP, IHC (p)
Validations
  • (7)
  • (6)
Cat. No. ABIN561263
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7155937
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7262825
Quantity 200 μL
Datasheet Datasheet

Recommended HIP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967472
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956610
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1137580
Quantity 96 tests
Datasheet Datasheet

Recommended HIP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306636
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306634
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420627
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HIP1 Products

Majeed, Vasudevan, Chen, Luo, Torres, Evans, Sharkey, Foraker, Wong, Esk, Freeman, Moffett, Keen, Brodsky: "Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration." in: Nature communications, Vol. 5, pp. 3891, (2014) (PubMed).

Fontaine, Bauer, Lin, Poorfarahani, Ybe: "Replacement of charged and polar residues in the coiled-coiled interface of huntingtin-interacting protein 1 (HIP1) causes aggregation and cell death." in: FEBS letters, Vol. 586, Issue 19, pp. 3030-6, (2012) (PubMed).

Choudhury, Raychaudhuri, Bhattacharyya: "Identification of HYPK-interacting proteins reveals involvement of HYPK in regulating cell growth, cell cycle, unfolded protein response and cell death." in: PLoS ONE, Vol. 7, Issue 12, pp. e51415, (2012) (PubMed).

Barker, Benovic: "G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4." in: Biochemistry, Vol. 50, Issue 32, pp. 6933-41, (2011) (PubMed).

Datta, Bhattacharyya: "Regulation of RE1 protein silencing transcription factor (REST) expression by HIP1 protein interactor (HIPPI)." in: The Journal of biological chemistry, Vol. 286, Issue 39, pp. 33759-69, (2011) (PubMed).

Datta, Choudhury, Lahiri, Bhattacharyya: "Genome wide gene expression regulation by HIP1 Protein Interactor, HIPPI: prediction and validation." in: BMC genomics, Vol. 12, pp. 463, (2011) (PubMed).

Banerjee, Datta, Majumder, Mukhopadhyay, Bhattacharyya: "Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1." in: Nucleic acids research, Vol. 38, Issue 3, pp. 878-92, (2010) (PubMed).

Bradley, Holland, Liu, Thomas, Hyun, Ross: "Huntingtin interacting protein 1 is a novel brain tumor marker that associates with epidermal growth factor receptor." in: Cancer research, Vol. 67, Issue 8, pp. 3609-15, (2007) (PubMed).

Bradley, Smith, Hyun, Lucas, Li, Antonuk, Joshi, Jin, Ross: "Aberrant Huntingtin interacting protein 1 in lymphoid malignancies." in: Cancer research, Vol. 67, Issue 18, pp. 8923-31, (2007) (PubMed).

Peng: "The T-box transcription factor T-bet in immunity and autoimmunity." in: Cellular & molecular immunology, Vol. 3, Issue 2, pp. 87-95, (2006) (PubMed).

Synonyms and alternative names related to HIP1

huntingtin interacting protein 1 (HIP1), Huntingtin interacting protein 1 (Hip1), huntingtin interacting protein 1 (Hip1), huntingtin interacting protein 1 (hip1), 2610109B09Rik, A930014B11Rik, CG10971, Dmel\\CG10971, E130315I21Rik, HIP-I, Hip1R, ILWEQ, mKIAA4113

Protein level used designations for HIP1

  • huntingtin-interacting protein 1
  • huntingtin-interacting protein I
  • CG10971-PA
  • CG10971-PB
  • Hip1-PA
  • Hip1-PB
  • huntingtin interacting protein 1
  • HIP-I
  • LOW QUALITY PROTEIN: huntingtin-interacting protein 1
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