HIF1AN 抗体
(Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011].
recommended
recommended
recommended
HIF1AN 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
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Find available monoclonal or polyclonal HIF1AN 抗体. Click on a link to go to the corresponding products.
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Validations
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Datasheet
Reactivity
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Application
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Cat. No.
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Datasheet
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Cat. No.
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Cat. No.
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WB, IHC, IP, IF, ChIP, IC
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Quantity
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Datasheet
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Reactivity
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Datasheet
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Reactivity
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Cat. No.
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Datasheet
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Quantity
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Datasheet
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Reactivity
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Quantity
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Datasheet
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Latest Publications for our HIF1AN 抗体
: "Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway." in: PLoS ONE, Vol. 14, Issue 2, pp. e0211244, (2019) (PubMed).: "Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1." in: Redox biology, Vol. 26, pp. 101265, (2019) (PubMed).
: "Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1." in: Science signaling, Vol. 9, Issue 430, pp. ra56, (2017) (PubMed).
: "miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages." in: Frontiers in immunology, Vol. 8, pp. 1327, (2017) (PubMed).
: "NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells." in: Scientific reports, Vol. 6, pp. 22784, (2016) (PubMed).
: "A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity." in: Molecular cancer research : MCR, Vol. 14, Issue 3, pp. 253-66, (2016) (PubMed).
: "Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel." in: Journal of cell science, Vol. 128, Issue 2, pp. 225-31, (2015) (PubMed).
: "Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 7, pp. 2814-27, (2015) (PubMed).
: "Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer." in: BMC cancer, Vol. 13, pp. 526, (2014) (PubMed).
: "Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2)." in: Journal of cell science, Vol. 126, Issue Pt 12, pp. 2629-40, (2013) (PubMed).
Aliases for HIF1AN 抗体
hypoxia inducible factor 1 alpha subunit inhibitor (HIF1AN) 抗体hypoxia-inducible factor 1, alpha subunit inhibitor (Hif1an) 抗体
hypoxia inducible factor 1, alpha subunit inhibitor (hif1an) 抗体
hypoxia-inducible factor 1, alpha subunit inhibitor S homeolog (hif1an.S) 抗体
hypoxia inducible factor 1 alpha subunit inhibitor (Hif1an) 抗体
2310046M24Rik 抗体
A830014H24Rik 抗体
cb728 抗体
FIH1 抗体
id:ibd5139 抗体
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