HFE2 产品
(Hemochromatosis Type 2 (Juvenile) (HFE2))
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The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq, Jul 2008].
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Featured HFE2 Categories
HFE2 抗体
High quality antibodies with extensive validation data.
HFE2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
HFE2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HFE2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7441934
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN566853
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
Cat. No.
ABIN530965
Quantity
100 μg
Datasheet
Datasheet
Recommended HFE2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (11)
- (1)
Cat. No.
ABIN6956455
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6956456
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6956454
Quantity
96 tests
Datasheet
Datasheet
Recommended HFE2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306581
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Synthetic
Validations
- (2)
Cat. No.
ABIN1880255
Quantity
200 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413832
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HFE2 Products
: "The functional role of hemojuvelin in acute ischemic stroke." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 40, Issue 6, pp. 1316-1327, (2021) (PubMed).: "Hemojuvelin Predicts Acute Kidney Injury and Poor Outcomes Following Cardiac Surgery." in: Scientific reports, Vol. 8, Issue 1, pp. 1938, (2018) (PubMed).
: "Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery." in: Critical care, Vol. 22, Issue 1, pp. 108, (2018) (PubMed).
: "Soluble hemojuvelin in transfused and untransfused thalassaemic subjects." in: European journal of haematology, Vol. 98, Issue 1, pp. 67-74, (2017) (PubMed).
: "The secret war against counterfeit science." in: Nature, Vol. 545, Issue 7653, pp. 148-150, (2017) (PubMed).
: "Hepcidin Levels Are Increased in Patients with Acute Ischemic Stroke: Preliminary Report." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 24, Issue 7, pp. 1570-6, (2015) (PubMed).
: "Bone marrow iron depletion is common in patients with coronary artery disease." in: International journal of cardiology, Vol. 182, pp. 517-22, (2015) (PubMed).
: "Iron Status and Inflammation in Early Stages of Chronic Kidney Disease." in: Kidney & blood pressure research, Vol. 40, Issue 4, pp. 366-73, (2015) (PubMed).
: "Hemojuvelin modulates iron stress during acute kidney injury: improved by furin inhibitor." in: Antioxidants & redox signaling, Vol. 20, Issue 8, pp. 1181-94, (2014) (PubMed).
: "The effects of iloprost on colonic anastomotic healing in rats under obstructive ileus conditions." in: The Journal of surgical research, Vol. 189, Issue 1, pp. 22-31, (2014) (PubMed).
Synonyms and alternative names related to HFE2
hemochromatosis type 2 (juvenile) (HFE2), hemochromatosis type 2 (juvenile) (Hfe2), hemochromatosis type 2 (hfe2), 2310035L15Rik, 5230400G09Rik, AI414844, AI789733, DKFZp468F2322, DL-M, hemojuvelin, HFE2, HFE2A, HJV, hjv, id:ibd3464, JH, RGMC, Rgmc, RGMr, wu:fb38f10, zgc:136698Protein level used designations for HFE2
- RGM domain family member C
- haemojuvelin
- hemochromatosis type 2 protein
- hemojuvelin
- repulsive guidance molecule c
- hemochromatosis type 2 (juvenile)
- hemochromatosis type 2 protein homolog
- repulsive guidance molecule C
- hemochromatosis type 2 (juvenile) (human homolog)
- RGM-like protein
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