HFE 产品
(Hemochromatosis (HFE))
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The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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Recommended HFE 抗体
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Reactivity
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
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Cat. No.
ABIN561252
Quantity
100 μg
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Datasheet
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Application
ELISA, ICC
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Cat. No.
ABIN969192
Quantity
100 μL
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Application
WB, FACS
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Cat. No.
ABIN516405
Quantity
50 μg
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Recommended HFE 蛋白
Latest Publications for our HFE Products
: "Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism." in: Oncotarget, Vol. 8, Issue 4, pp. 6376-6398, (2016) (PubMed).: "Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer." in: PLoS ONE, Vol. 8, Issue 8, pp. e74075, (2013) (PubMed).
: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).
: "HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 4, Issue 8, pp. 1331-7, (2009) (PubMed).
Synonyms and alternative names related to HFE
hemochromatosis (HFE), hemochromatosis (Hfe), HFE1, HH, HLA-H, MR2, MVCD7, TFQTL2Protein level used designations for HFE
- MHC class I-like protein HFE
- hereditary hemochromatosis protein
- hereditary hemochromatosis protein HLA-H
- high Fe
- RT1-CAFE
- hereditary hemochromatosis protein homolog
- hemochromatosis protein
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