HEY2 产品
(Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))
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This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
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Featured HEY2 Categories
Recommended HEY2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN949119
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6262369
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN652095
Quantity
400 μL
Datasheet
Datasheet
Recommended HEY2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306574
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306572
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3081431
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our HEY2 Products
: "Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site." in: Circulation research, Vol. 102, Issue 6, pp. 661-8, (2008) (PubMed).: "Characterization of hey bHLH genes in teleost fish." in: Development genes and evolution, Vol. 213, Issue 11, pp. 541-53, (2003) (PubMed).
: "Gridlock signalling pathway fashions the first embryonic artery." in: Nature, Vol. 414, Issue 6860, pp. 216-20, (2001) (PubMed).
: "gridlock, an HLH gene required for assembly of the aorta in zebrafish." in: Science (New York, N.Y.), Vol. 287, Issue 5459, pp. 1820-4, (2000) (PubMed).
Synonyms and alternative names related to HEY2
hes related family bHLH transcription factor with YRPW motif 2 (HEY2), hairy/enhancer-of-split related with YRPW motif 2 (Hey2), hes-related family bHLH transcription factor with YRPW motif 2 (hey2), hes-related family bHLH transcription factor with YRPW motif 2 (Hey2), bHLHb32, CHF1, GRIDLOCK, GRL, grl, HERP1, Herp1, HESR2, hesr2, HRT2, Hrt2, zgc:136746Protein level used designations for HEY2
- hairy/enhancer-of-split related with YRPW motif protein 2
- HES-related repressor protein 1
- HES-related repressor protein 2
- HESR-2
- HRT-2
- cardiovascular basic helix-loop-helix factor 1
- cardiovascular helix-loop-helix factor 1
- class B basic helix-loop-helix protein 32
- hCHF1
- hHRT2
- hairy and enhancer of split-related protein 2
- hairy-related transcription factor 2
- protein gridlock homolog
- Hairy-E(spl)-related with YRPW motif 2
- hairy and enhancer of split related 2
- mHRT2
- Herp2
- gridlock
- protein gridlock
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