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Hepcidin 产品

(Hepcidin Antimicrobial Peptide (HAMP))
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].

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Featured Hepcidin Categories

Hepcidin 抗体

High quality antibodies with extensive validation data.

Hepcidin ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Hepcidin 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Hepcidin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7434458
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7427882
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7434461
Quantity 100 μL
Datasheet Datasheet

Recommended Hepcidin ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (14)
  • (1)
Cat. No. ABIN6956502
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (16)
  • (1)
Cat. No. ABIN6956508
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6963616
Quantity 96 tests
Datasheet Datasheet

Recommended Hepcidin 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7274793
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7274792
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123314
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Hepcidin Products

Pászti-Gere, Szombath, Gütschow, Steinmetzer, Székács: "3-Amidinophenylalanine-derived matriptase inhibitors can modulate hepcidin production in vitro." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 393, Issue 3, pp. 511-520, (2021) (PubMed).

Chen, Ma, Liu, Hao, Yang, Liu: "H2 O2 induces oxidative stress damage through the BMP-6/SMAD/hepcidin axis." in: Development, growth & differentiation, Vol. 62, Issue 2, pp. 139-146, (2020) (PubMed).

Floege, Funk, Ketteler, Rastogi, Walpen, Covic, Sprague: "Iron kinetics following treatment with sucroferric oxyhydroxide or ferric citrate in healthy rats and models of anaemia, iron overload or inflammation." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 35, Issue 6, pp. 946-954, (2020) (PubMed).

Rajamanickam, Leela, Suganya, Basha, Parthiban, Pazhanivel, Mangala Gowri: "Expression of iron regulatory proteins in full-term swine placenta." in: Reproduction in domestic animals = Zuchthygiene, Vol. 55, Issue 8, pp. 931-942, (2020) (PubMed).

Gromadzka, Wierzbicka, Litwin, Przybyłkowski: "Difference in iron metabolism may partly explain sex-related variability in the manifestation of Wilson's disease." in: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), Vol. 62, pp. 126637, (2020) (PubMed).

Adel, Mantawy, El-Sherbiny, El-Demerdash: "Iron chelation by deferasirox confers protection against concanavalin A-induced liver fibrosis: A mechanistic approach." in: Toxicology and applied pharmacology, Vol. 382, pp. 114748, (2020) (PubMed).

Barna, Pomothy, Paréj, Pásztiné Gere: "Investigation of sphingosin-1-phosphate-triggered matriptase activation using a rat primary hepatocyte model." in: Acta veterinaria Hungarica, Vol. 67, Issue 4, pp. 578-587, (2020) (PubMed).

Kim, Kim, Lim, Yang, Park, Kim, Jeong, Choi, Kim: "Epigallocatechin-3-Gallate (EGCG)-Inducible SMILE Inhibits STAT3-Mediated Hepcidin Gene Expression." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 6, (2020) (PubMed).

Nienaber, Baumgartner, Dolman, Ozturk, Zandberg, Hayford, Brombacher, Blaauw, Parihar, Smuts, Malan: "Omega-3 Fatty Acid and Iron Supplementation Alone, but Not in Combination, Lower Inflammation and Anemia of Infection in Mycobacterium tuberculosis-Infected Mice." in: Nutrients, Vol. 12, Issue 9, (2020) (PubMed).

Blanchette-Farra, Kita, Konstorum, Tesfay, Lemler, Hegde, Claffey, Torti, Torti: "Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer." in: Oncogene, Vol. 37, Issue 29, pp. 4013-4032, (2019) (PubMed).

Synonyms and alternative names related to Hepcidin

hepcidin antimicrobial peptide (HAMP), hepcidin antimicrobial peptide (Hamp), hepcidin antimicrobial peptide (hamp), hepcidin-like (LOC100135935), hepcidin-1 (LOC106584587), Ham percentage (HAMP), HAMP, Hamp1, hamp1, hep1, HEPC, Hepc, Hepc1, Hepcidin, hepcidin, HFE2B, LEAP1, PLTR

Protein level used designations for Hepcidin

  • hepcidin
  • liver-expressed antimicrobial peptide 1
  • putative liver tumor regressor
  • hepcidin antimicrobial peptide 1
  • hepcidin antimicrobial peptide
  • antimicrobial peptide
  • hepcidin-1
  • iron regulatory peptide
  • preprohepcidin 1
  • antimicrobial peptide hepcidin
  • putative hepcidin antibacterial peptide
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