HECW1 抗体
(HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1))
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
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HECW1 抗体
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Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7151033
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
ELISA, WB, IHC
Validations
- (1)
Cat. No.
ABIN6262201
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7151036
Quantity
100 μL
Datasheet
Datasheet
Synonyms and alternative names related to HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (HECW1), HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (Hecw1), 9330116H24Rik, AV273951, E130207I19Rik, NEDL1, Nedl1Protein level used designations for HECW1
- E3 ubiquitin-protein ligase HECW1
- HECT type E3 ubiquitin ligase
- HECT, C2 and WW domain-containing protein 1
- NEDD4-like E3 ubiquitin-protein ligase 1
- NEDD4-like ubiquitin-protein ligase 1
- mNEDL1
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