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HECW1 抗体

(HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1))
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.

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Featured HECW1 Categories

HECW1 抗体

High quality antibodies with extensive validation data.

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Synonyms and alternative names related to HECW1

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (HECW1), HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (Hecw1), 9330116H24Rik, AV273951, E130207I19Rik, NEDL1, Nedl1

Protein level used designations for HECW1

  • E3 ubiquitin-protein ligase HECW1
  • HECT type E3 ubiquitin ligase
  • HECT, C2 and WW domain-containing protein 1
  • NEDD4-like E3 ubiquitin-protein ligase 1
  • NEDD4-like ubiquitin-protein ligase 1
  • mNEDL1
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