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HDAC6 产品

(Histone Deacetylase 6 (HDAC6))

Categories

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008].

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Featured HDAC6 Categories

HDAC6 抗体

High quality antibodies with extensive validation data.

HDAC6 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

HDAC6 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HDAC6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7439288
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (7)
Cat. No. ABIN1498618
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Rat
Application WB, IF, FACS
Validations
  • (6)
Cat. No. ABIN1498620
Quantity 100 μL
Datasheet Datasheet

Recommended HDAC6 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956577
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967439
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956578
Quantity 96 tests
Datasheet Datasheet

Recommended HDAC6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306458
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306460
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398212
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HDAC6 Products

Liang, Qi, Lai, Xie, Wang, Zhang, Lin, Jv, Li, Wang, Zhang, Chen, Qiu, Li, Li, Ye, Liu, Liang, Shi, Wang: "HDAC6-mediated α-tubulin deacetylation suppresses autophagy and enhances motility of podocytes in diabetic nephropathy." in: Journal of cellular and molecular medicine, Vol. 24, Issue 19, pp. 11558-11572, (2020) (PubMed).

Ding, Kang, Tang, Zhao: "Inhibition of HDAC6 expression decreases brain injury induced by APOE4 and Aβ co‑aggregation in rats." in: Molecular medicine reports, (2019) (PubMed).

Menden, Xia, Mabry, Noel-MacDonnell, Rajasingh, Ye, Sampath: "Histone deacetylase 6 regulates endothelial MyD88-dependent canonical TLR signaling, lung inflammation, and alveolar remodeling in the developing lung." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 317, Issue 3, pp. L332-L346, (2019) (PubMed).

Sirchia, Faversani, Rovina, Russo, Paganini, Savi, Augello, Rosso, Del Gobbo, Tabano, Bosari, Miozzo: "Epigenetic effects of chromatin remodeling agents on organotypic cultures." in: Epigenomics, Vol. 8, Issue 3, pp. 341-58, (2016) (PubMed).

Wang, Hu, Tang, Xie: "HDAC6-mediated EGFR stabilization and activation restrict cell response to sorafenib in non-small cell lung cancer cells." in: Medical oncology (Northwood, London, England), Vol. 33, Issue 5, pp. 50, (2016) (PubMed).

Ran, Yang, Li, Liu, Zhou: "Deacetylation of ?-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly." in: Scientific reports, Vol. 5, pp. 12917, (2015) (PubMed).

Yu, Diao, Wang, Lin, Yu, Lu, Xu, Li, Shi, Zhao, Zhou, Zhang: "Acetylproteomic analysis reveals functional implications of lysine acetylation in human spermatozoa (sperm)." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 4, pp. 1009-23, (2015) (PubMed).

Pacheco, Berra, Morais, Sciani, Branco, Bosch, Chudzinski-Tavassi: "Dynein function and protein clearance changes in tumor cells induced by a Kunitz-type molecule, Amblyomin-X." in: PLoS ONE, Vol. 9, Issue 12, pp. e111907, (2014) (PubMed).

Zhang, Xiang, Joo, Wang, Williams, Liu, Hu, Tong, Haakenson, Wang, Zhang, Pavlovicz, Jones, Schmidt, Tang, Dong, Shan, Fang, Radhakrishnan, Glazer, Matthias, Koomen, Seto, Bepler, Nicosia, Chen, Li et al.: "HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα. ..." in: Molecular cell, Vol. 55, Issue 1, pp. 31-46, (2014) (PubMed).

Wang, Chen, Zhang, Zhang, Zhuo, Liu, Jiang, Zhang: "PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry." in: Journal of cell science, Vol. 126, Issue Pt 6, pp. 1355-65, (2013) (PubMed).

Synonyms and alternative names related to HDAC6

histone deacetylase 6 (HDAC6), histone deacetylase 6 (Hdac6), Histone deacetylase 6 (HDAC6), histone deacetylase 6 L homeolog (hdac6.L), histone deacetylase 6 (hdac6), GD17207 gene product from transcript GD17207-RB (Dsim\HDAC6), histone deacetylase 6 (PTRG_03035), histone deacetylase 6 (HDA6), Histone DeAcetylase (hda-6), ATHDA6, AXE1, CG6170, DHDAC2, dHDAC2, dHDAC6, Dmel\\CG6170, dmHDA404, DmHDAC2, DsimGD17207, dsim_GLEANR_17355, GD17207, HD6, Hd6, HDAC, HDAC2, Hdac5, hdac6, HDAC6, HISTONE DEACETYLASE 6, histone deacetylase 6, MDC12.7, MDC12_7, MGC53140, mHDA2, RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1, RPD3B, RTS1, Sfc6, SIL1, wu:fc31d02

Protein level used designations for HDAC6

  • histone deacetylase 5
  • histone deacetylase mHDA2
  • scurfy candidate 6
  • CG6170-PA
  • CG6170-PB
  • CG6170-PC
  • CG6170-PD
  • CG6170-PE
  • CG6170-PF
  • CG6170-PG
  • HDAC6-PA
  • HDAC6-PB
  • HDAC6-PC
  • HDAC6-PD
  • HDAC6-PE
  • HDAC6-PF
  • HDAC6-PG
  • histone deacetylase 6
  • histone deacetylase HDA2
  • DsimGD17207-PA
  • DsimHDAC6-PA
  • GD17207-PA
  • HDAC6
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