HDAC4/HDAC5/HDAC9 抗体
(HDAC4,HDAC5,HDAC9)
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].
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Recommended HDAC4/HDAC5/HDAC9 抗体
Product
Reactivity
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Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, ELISA
Validations
- (3)
Cat. No.
ABIN7138137
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA
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Cat. No.
ABIN7138509
Quantity
100 μL
Datasheet
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Reactivity
Human, Mouse
Application
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ABIN319389
Quantity
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Datasheet
Datasheet
Latest Publications for our HDAC4/HDAC5/HDAC9 Products
: "KDM5 interacts with Foxo to modulate cellular levels of oxidative stress." in: PLoS genetics, Vol. 10, Issue 10, pp. e1004676, (2014) (PubMed).: "Targeted histone deacetylase inhibition for cancer therapy." in: Current cancer drug targets, Vol. 4, Issue 2, pp. 205-18, (2004) (PubMed).
: "Histone deacetylases: unique players in shaping the epigenetic histone code." in: Annals of the New York Academy of Sciences, Vol. 983, pp. 84-100, (2003) (PubMed).
: "Structure and function of histone acetyltransferases." in: Cellular and molecular life sciences : CMLS, Vol. 58, Issue 5-6, pp. 693-703, (2001) (PubMed).
Synonyms and alternative names related to HDAC4/HDAC5/HDAC9
histone deacetylase 4 (HDAC4), AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACAProtein level used designations for HDAC4/HDAC5/HDAC9
- histone deacetylase A
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