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HCFC1 产品

(Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))
This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].

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Featured HCFC1 Categories

HCFC1 抗体

High quality antibodies with extensive validation data.

HCFC1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

HCFC1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HCFC1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN5013712
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (4)
Cat. No. ABIN2780671
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7155909
Quantity 100 μg
Datasheet Datasheet

Recommended HCFC1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1137529
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1137530
Quantity 96 tests
Datasheet Datasheet

Recommended HCFC1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306416
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306414
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418764
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HCFC1 Products

Hsu, Arand, Chaikovsky, Mooney, Demeter, Brison, Oliverio, Vogel, Rubin, Jackson, Sage: "E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family." in: Nature communications, Vol. 10, Issue 1, pp. 2939, (2019) (PubMed).

Kang, Piao, Ryu, Kang, Chang, Keum, Hyun: "Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells." in: Oncotarget, Vol. 7, Issue 26, pp. 40594-40620, (2016) (PubMed).

Parker, Palchaudhuri, Yin, Wei, Chakravarti: "A transcriptional regulatory role of the THAP11-HCF-1 complex in colon cancer cell function." in: Molecular and cellular biology, Vol. 32, Issue 9, pp. 1654-70, (2012) (PubMed).

Rizki, Iwata, Li, Riedel, Picard, Jan, Murphy, Lee: "The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO." in: PLoS genetics, Vol. 7, Issue 9, pp. e1002235, (2011) (PubMed).

Yu, Mashtalir, Daou, Hammond-Martel, Ross, Sui, Hart, Rauscher, Drobetsky, Milot, Shi, Affar: "The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression." in: Molecular and cellular biology, Vol. 30, Issue 21, pp. 5071-85, (2010) (PubMed).

Synonyms and alternative names related to HCFC1

host cell factor C1 (HCFC1), host cell factor C1 (Hcfc1), host cell factor C1a (hcfc1a), host cell factor (LOC5571204), host cell factor C1 (CpipJ_CPIJ014908), host cell factor C1 (VP16-accessory protein) (HCFC1), AW060991, CFF, fc61g09, HCF, HCF-1, HCF1, hcfc1, HCFC1, HFC1, im:7159458, MRX3, RGD1563804, VCAF, wu:fc61g09, wu:fj40c12

Protein level used designations for HCFC1

  • C1 factor
  • HCF
  • VP16 accessory protein
  • host cell factor 1
  • VP16-accessory protein
  • etID52682.11
  • host cell factor C1
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