H2AFY 产品
(H2A Histone Family, Member Y (H2AFY))
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Latest Publications for our H2AFY Products
: "Inhibition of osteosarcoma cell progression by MacroH2A via the downregulation of cyclin D and cyclin‑dependent kinase genes." in: Molecular medicine reports, Vol. 11, Issue 3, pp. 1905-10, (2014) (PubMed).Synonyms and alternative names related to H2AFY
core histone macro-H2A.1 (LOC100230612), H2A histone family, member Y (H2AFY), H2A histone family member Y (H2AFY), core histone macro-H2A.1 (LOC481514), H2A histone family, member Y (H2afy), H2A histone family, member Y (h2afy), H2A histone family member Y L homeolog (h2afy.L), H2A.y, h2a.y, H2A/y, h2a/y, H2AF12M, h2af12m, H2AFJ, h2afj, macroh2a, macroH2A1, MACROH2A1.1, macroH2A1.2, mH2A1, mH2a1, mh2a1, wu:fa93c12, zgc:136891Protein level used designations for H2AFY
- H2A histone family, member Y
- H2A.y
- H2A/y
- core histone macro-H2A.1
- histone macroH2A1
- histone macroH2A1.2
- mH2A1
- histone H2A.y
- histone macroH2A1.1
- medulloblastoma antigen MU-MB-50.205
- MACROH2A1.2
- H2A1
- fa93c12
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