HARS1/Jo-1 产品
(Histidyl-tRNA Synthetase (HARS1))
Categories
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
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Featured HARS1/Jo-1 Categories
HARS1/Jo-1 抗体
High quality antibodies with extensive validation data.
HARS1/Jo-1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
HARS1/Jo-1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HARS1/Jo-1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN516353
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IP
Validations
- (4)
Cat. No.
ABIN7155257
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN516350
Quantity
50 μL
Datasheet
Datasheet
Recommended HARS1/Jo-1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967424
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1136754
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1136755
Quantity
96 tests
Datasheet
Datasheet
Recommended HARS1/Jo-1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306360
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306358
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123338
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our HARS1/Jo-1 Products
: "Comparison of histidine recognition in human and trypanosomatid histidyl-tRNA synthetases." in: Biochimie, Vol. 106, pp. 111-20, (2014) (PubMed).: "Target specificity of an autoreactive pathogenic human γδ-T cell receptor in myositis." in: The Journal of biological chemistry, Vol. 287, Issue 25, pp. 20986-95, (2012) (PubMed).
: "New mortalin and histidyl tRNA synthetase isoforms point out a pitfall in proteomic analysis of Egr1 genetically modified mice." in: Proteomics, Vol. 7, Issue 2, pp. 289-98, (2007) (PubMed).
: "Novel conformation of histidyl-transfer RNA synthetase in the lung: the target tissue in Jo-1 autoantibody-associated myositis." in: Arthritis and rheumatism, Vol. 56, Issue 8, pp. 2729-39, (2007) (PubMed).
: "TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 13, pp. 7626-31, (2003) (PubMed).
Synonyms and alternative names related to HARS1/Jo-1
histidyl-tRNA synthetase (HARS), histidyl-tRNA synthetase (Hars), Dnd1, HARSL, HRS, MMHRS, USH3BProtein level used designations for HARS1/Jo-1
- HisRS
- histidine translase
- histidine--tRNA ligase, cytoplasmic
- hisRS
- histidine tRNA ligase
- histidyl-tRNA synthetase, cytoplasmic
- dead end homolog 1
- Histidyl-tRNA synthetase, cytoplasmic
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