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Hairy and Enhancer of Split 4 蛋白

(Hairy and Enhancer of Split 4 (HES4))
Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. Promotes floor plate development and prechordal plate development. Required for lens development as early as the stage of lens field formation, partly through regulation of gene expression of the cell cycle inhibitor cdknx/p27(xic1). Required for formation of the neural crest downstream of multiple signaling pathways, and acts at the neural plate border via both DNA-binding dependent and independent mechanisms. Also acts via repressor- dependent and repressor-independent mechanisms in early gastrulae to establish the prospective anterior prechordal mesoderm identity in the Spemann organizer\; induces specific genes independently from direct transcriptional regulation, and represses the genes specific for neighboring tissues through direct transcriptional repression. Modulates lateral inhibition during notch signaling and regulates the cell context dependent effects of notch (which can have inhibitory, permissive or enhancing roles in muscle or neural differentiation). Inhibits myogenesis (By similarity).
HES4 Protein (AA 1-221) (GST tag) HES4 Protein (AA 1-221) (GST tag) HES4 Protein (AA 1-221) (GST tag) (ABIN1306551)

HES4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

HES4 Protein (AA 1-221) (Strep Tag) (ABIN3081428)

HES4 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

HES4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) HES4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) HES4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2722664)

HES4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

Hairy and Enhancer of Split 4 蛋白 by Origin

Find Hairy and Enhancer of Split 4 蛋白 for a variety of species such as anti-Human Hairy and Enhancer of Split 4, anti-Xenopus laevis Hairy and Enhancer of Split 4. The species listed below are among those available. Click on a link to go to the corresponding products.

Hairy and Enhancer of Split 4 蛋白 by Source

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Hairy and Enhancer of Split 4 蛋白 by 蛋白类型

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Hairy and Enhancer of Split 4 蛋白 by 应用范围

Find Hairy and Enhancer of Split 4 蛋白 validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Hairy and Enhancer of Split 4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306551
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3081428
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2722664
Quantity 20 μg
Datasheet Datasheet
Reactivity Xenopus laevis
Source Yeast
Validations
Cat. No. ABIN1639349
Quantity 1 mg
Datasheet Datasheet
Reactivity Xenopus laevis
Source Yeast
Validations
Cat. No. ABIN1640267
Quantity 1 mg
Datasheet Datasheet

Aliases for Hairy and Enhancer of Split 4 蛋白

hes family bHLH transcription factor 4 (HES4) 蛋白
hes family bHLH transcription factor 4 (hes4) 蛋白
hes family bHLH transcription factor 4 L homeolog (hes4.L) 蛋白
hes family bHLH transcription factor 4 S homeolog (hes4.S) 蛋白
bHLHb42 蛋白
hairy2 蛋白
hairy2a 蛋白
hairy2b 蛋白
hes1 蛋白
hes4a 蛋白
hes4b 蛋白
Xhairy2 蛋白
XHairy2a 蛋白
Xhairy2a 蛋白
Xhairy2b 蛋白
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