GZMB 产品
(Granzyme B (GZMB))
Categories
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008].
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Featured GZMB Categories
GZMB 抗体
High quality antibodies with extensive validation data.
GZMB ELISA试剂盒
Reliable ELISA kits for a wide range of species.
GZMB 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GZMB 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7432145
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, StM
Validations
- (5)
Cat. No.
ABIN6939591
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
- (1)
- (3)
Cat. No.
ABIN675354
Quantity
100 μL
Datasheet
Datasheet
Recommended GZMB ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956298
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956299
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956300
Quantity
96 tests
Datasheet
Datasheet
Recommended GZMB 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306264
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306262
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320540
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our GZMB Products
: "Granzyme B levels and granzyme B polymorphisms in peripheral blood of patients with endometriosis: a preliminary study." in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 41, Issue 1, pp. 94-99, (2021) (PubMed).: "A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors." in: Theranostics, Vol. 9, Issue 25, pp. 7616-7627, (2020) (PubMed).
: "Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal. ..." in: Nature immunology, Vol. 21, Issue 5, pp. 555-566, (2020) (PubMed).
: "Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells." in: Immunity, Vol. 48, Issue 5, pp. 1029-1045.e5, (2019) (PubMed).
: "Transcriptomic analysis of human IL-7 receptor alpha low and high effector memory CD8+ T cells reveals an age-associated signature linked to influenza vaccine response in older adults." in: Aging cell, Vol. 18, Issue 4, pp. e12960, (2019) (PubMed).
: "Interleukin-21 Regulates Natural Killer Cell Responses During Mycobacterium tuberculosis Infection." in: The Journal of infectious diseases, Vol. 217, Issue 8, pp. 1323-1333, (2019) (PubMed).
: "Efficient ADCC killing of meningioma by avelumab and a high-affinity natural killer cell line, haNK." in: JCI insight, Vol. 4, Issue 20, (2019) (PubMed).
: "Granzyme B induced by Rv0140 antigen discriminates latently infected from active tuberculosis individuals." in: Journal of leukocyte biology, Vol. 105, Issue 2, pp. 297-306, (2019) (PubMed).
: "CMV-infected kidney grafts drive the expansion of blood-borne CMV-specific T cells restricted by shared class I HLA molecules via presentation on donor cells." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 18, Issue 8, pp. 1904-1913, (2019) (PubMed).
: "Urothelial bladder cancer may suppress perforin expression in CD8+ T cells by an ICAM-1/TGFβ2 mediated pathway." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200079, (2019) (PubMed).
Synonyms and alternative names related to GZMB
granzyme B (GZMB), CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECTProtein level used designations for GZMB
- C11
- CTLA-1
- T-cell serine protease 1-3E
- cathepsin G-like 1
- cytotoxic T-lymphocyte proteinase 2
- cytotoxic serine protease B
- fragmentin 2
- fragmentin-2
- granzyme B
- human lymphocyte protein
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