GUT2 Protein (AA 43-600) (His tag)
GUT2
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, ELISA
-
- 抗原
- GUT2 (Mitochondrial Glycerol-3-Phosphate Dehydrogenase (GUT2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 43-600
- 宿主
- 人
- 资源
- 大肠杆菌（E. Coli）
- 标记
- This GUT2 protein is labelled with His tag.
- 应用范围
- Western Blotting (WB), ELISA
- 原理
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase (mGPD)
- 序列
- ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS VQAAEEALPR IVELMGRELN WDDYKKQEQL ETARKFLY
- 产品特性
- recombinant mGPD comprises a 558 amino acid fragment (43-600) corresponding to the GlpA domain fragment of the mature mGPD protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
- 纯度
- > 95 %
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- 20 mM Tris HCl pH 8, 1 mM EDTA, 50 % Glycerol
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C
-
- 抗原
- GUT2 (Mitochondrial Glycerol-3-Phosphate Dehydrogenase (GUT2))
- 别名
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase
- 背景
- Mitochondrial glycerol-3-phosphate dehydrogenase (mGPD) is a Ca2+ -sensitive, FAD-binding protein, located on the outer surface of the inner mitochondrial membrane. mGPD catalyses the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Two isoforms have been described for mGPD. Isoform 1 comprises 727aa residues, whereas isoform 2 lacks 126aa residues of the N-terminus. Deficiency of mGPD appears to contribute to the impairment of glucose-stimulated insulin release in several animal models of non-insulin dependent diabetes mellitus.,Glycerol-3-Phosphate Dehydrogenase 2, GPD2, Glycerophosphate Dehydrognase-2 Ca(2+ ) - Responsive Mitochondrial FAD-Linked, Mitochondrial GPD, GPDM, GPD-M, GPDH-M, mtGPD, GDH2.
- 分子量
- 66.26 kDa
- UniProt
- P43304
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