GSK3 beta 产品
(Glycogen Synthase Kinase 3 beta (GSK3b))
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The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].
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Featured GSK3 beta Categories
GSK3 beta 抗体
High quality antibodies with extensive validation data.
Recommended GSK3 beta 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IP
Validations
- (3)
Cat. No.
ABIN6241761
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN6243417
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN6266341
Quantity
100 μL
Datasheet
Datasheet
Recommended GSK3 beta 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7495130
Quantity
200 μg
Datasheet
Datasheet
Latest Publications for our GSK3 beta Products
: "Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway." in: Pharmacological research, Vol. 130, pp. 466-480, (2019) (PubMed).: "Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β." in: Neuroscience letters, Vol. 687, pp. 207-215, (2019) (PubMed).
: "Musashi 1-positive cells derived from mouse embryonic stem cells treated with LY294002 are prone to differentiate into intestinal epithelial-like tissues." in: International journal of molecular medicine, Vol. 43, Issue 6, pp. 2471-2480, (2019) (PubMed).
: "GSK-3 inhibition through GLP-1R allosteric activation mediates the neurogenesis promoting effect of P7C3 after cerebral ischemic/reperfusional injury in mice." in: Toxicology and applied pharmacology, Vol. 357, pp. 88-105, (2019) (PubMed).
: "Evidence of microglial activation following exposure to serum from first-onset drug-naïve schizophrenia patients." in: Brain, behavior, and immunity, Vol. 67, pp. 364-373, (2018) (PubMed).
: "ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3β/β-catenin signaling pathway." in: Oncotarget, Vol. 7, Issue 40, pp. 65374-65388, (2018) (PubMed).
: "α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway." in: Oncogenesis, Vol. 6, Issue 5, pp. e343, (2018) (PubMed).
: "MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation." in: Cell death and differentiation, Vol. 24, Issue 12, pp. 2161-2172, (2018) (PubMed).
: "AMPK/GSK3β/β-catenin cascade-triggered overexpression of CEMIP promotes migration and invasion in anoikis-resistant prostate cancer cells by enhancing metabolic reprogramming." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 7, pp. 3924-3935, (2018) (PubMed).
: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." in: Marine drugs, Vol. 16, Issue 3, (2018) (PubMed).
Synonyms and alternative names related to GSK3 beta
glycogen synthase kinase 3 beta (GSK3B), glycogen synthase kinase 3 beta (Gsk3b), glycogen synthase kinase 3 beta (gsk3b), glycogen synthase kinase 3 beta L homeolog (gsk3b.L), 7330414F15Rik, 8430431H08Rik, C86142, fk80d11, GSK-3, gsk-3, GSK-3beta, GSK-3[b], GSK3, gsk3, gsk3-beta, GSK3beta, gsk3beta, wu:fb68h05, wu:fk80d11, xgsk-3Protein level used designations for GSK3 beta
- GSK-3 beta
- GSK3beta isoform
- glycogen synthase kinase-3 beta
- serine/threonine-protein kinase GSK3B
- FA
- factor A
- GSK-3beta
- glycogen synthase kinase 3 beta variant 1
- glycogen synthase kinase 3 beta variant 2
- glycogen synthase kinase 3 beta variant 3
- glycogen synthase kinase 3 beta variant 4
- fb68h05
- intracellular kinase
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