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GRP78 产品

(Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010].

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Featured GRP78 Categories

GRP78 抗体

High quality antibodies with extensive validation data.

GRP78 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GRP78 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GRP78 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
  • (8)
Cat. No. ABIN3020763
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IF, ICC, IP
Validations
  • (2)
  • (6)
Cat. No. ABIN361825
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, ICC, IP, IHC (p)
Validations
  • (2)
  • (9)
Cat. No. ABIN2855429
Quantity 100 μL
Datasheet Datasheet

Recommended GRP78 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956416
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967297
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956415
Quantity 96 tests
Datasheet Datasheet

Recommended GRP78 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1307202
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (4)
  • (1)
Cat. No. ABIN1686700
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Hi-5 Cells
Validations
  • (1)
Cat. No. ABIN667294
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GRP78 Products

Ye, Zeng, Ling, Ma, Chen, Lin, Li, Pan: "Inhibition of IP3R/Ca2+ Dysregulation Protects Mice From Ventilator-Induced Lung Injury via Endoplasmic Reticulum and Mitochondrial Pathways." in: Frontiers in immunology, Vol. 12, pp. 729094, (2021) (PubMed).

Cai, Han, Hu, Zhao, He, Chen, Sun, Yuan, Li, Yang, Kong, Kong: "Metformin attenuates the D‑galactose‑induced aging process via the UPR through the AMPK/ERK1/2 signaling pathways." in: International journal of molecular medicine, Vol. 45, Issue 3, pp. 715-730, (2020) (PubMed).

Griffiths, Del Bel, Wilk, Brill: "Cellular homeostasis in the Drosophila retina requires the lipid phosphatase Sac1." in: Molecular biology of the cell, Vol. 31, Issue 11, pp. 1183-1199, (2020) (PubMed).

Haenig, Atias, Taylor, Mazza, Schaefer, Russ, Riechers, Jain, Coughlin, Fontaine, Freibaum, Brusendorf, Zenkner, Porras, Stroedicke, Schnoegl, Arnsburg, Boeddrich, Pigazzini, Heutink, Taylor et al.: "Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. ..." in: Cell reports, Vol. 32, Issue 7, pp. 108050, (2020) (PubMed).

Martin, de Witte, Maurice, Gammaitoni, Farfel, Galer: "Fenfluramine acts as a positive modulator of sigma-1 receptors." in: Epilepsy & behavior : E&B, Vol. 105, pp. 106989, (2020) (PubMed).

Hu, Yang, Li, Wang, Cheng, Yang, Li, Deng, Liang, Yin, Xie, Tan: "Maternal Diet-Induced Obesity Compromises Oxidative Stress Status and Angiogenesis in the Porcine Placenta by Upregulating Nox2 Expression." in: Oxidative medicine and cellular longevity, Vol. 2019, pp. 2481592, (2020) (PubMed).

Chu, Chan, Zhang, Wang, Yuan, Zhou, Au-Yeung, Sze, Yang, Shuai, Hou, Li, Zhao, Poon, Leung, Yeung, Yan, Lu, Jin, Gao, Chan, Yuen: "Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells." in: The Journal of biological chemistry, Vol. 293, Issue 30, pp. 11709-11726, (2019) (PubMed).

Hong, Tseng, Wala, Kim, Kynnap, Doshi, Kugener, Sandoval, Howard, Li, Yang, Tillgren, Ghandi, Sayeed, Deasy, Ward, McSteen, Labella, Keskula, Tracy, Connor, Clinton, Church, Crompton, Janeway et al.: "Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition. ..." in: eLife, Vol. 8, (2019) (PubMed).

Subramanian, Capalbo, Iyengar, Rizzo, di Campli, Di Martino, Lo Monte, Beccari, Yerudkar, Del Vecchio, Glielmo, Turacchio, Pirozzi, Kim, Henklein, Cancino, Parashuraman, Diviani, Fanelli, Sallese et al.: "Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum. ..." in: Cell, Vol. 176, Issue 6, pp. 1461-1476.e23, (2019) (PubMed).

Xia, Ji, Xu, Lin, Wang, Xia, Lv, Song, Ma, Chen: "Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress." in: Cell death & disease, Vol. 8, Issue 7, pp. e2957, (2018) (PubMed).

Synonyms and alternative names related to GRP78

78 kDa glucose-regulated protein (CpipJ_CPIJ003550), heat shock protein family A (Hsp70) member 5 (HSPA5), 78 kDa glucose-regulated protein (grp78), BiP/GRP78 (LOC100533358), glucose-regulated protein 78 (BiP/grp78), glucose-regulated protein 78 (Tc00.1047053506585.40), glucose-regulated protein 78 (Tb11.02.5450), glucose-regulated protein 78 (Tb11.02.5500), putative glucose-regulated protein 78 (LMJF_28_1200), Hsp70 family ATPase KAR2 (KAR2), 78 kDa glucose-regulated protein (LOC100135840), heat shock protein family A (Hsp70) member 5 S homeolog (hspa5.S), heat shock 70 kDa protein 5a (hspa5), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5), heat shock protein family A (Hsp70) member 5 (Hspa5), heat shock protein 5 (Hspa5), heat shock protein family A member 5 (Hspa5), heat shock protein 5 (hspa5), AL022860, AU019543, baffled, BiP, BIP, Bip, cb865, D2Wsu17e, D2Wsu141e, fb60h09, fi36d04, GRP-78, GRP78, grp78, Grp78, Hsce70, hspa5a, mBiP, MIF2, SEZ-7, Sez7, wu:fb60h09, wu:fi36d04, zgc:55994, zgc:77606

Protein level used designations for GRP78

  • 78 kDa glucose-regulated protein
  • GRP-78
  • heat shock 70 kDa protein 5
  • Protein 1603
  • 78 kDa glucose-regulated protein homolog
  • luminal-binding protein
  • glucose-regulated protein 78
  • glucose-regulated protein 78kDa
  • heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
  • GRP 78
  • biP
  • heavy-chain binding protein BiP
  • immunoglobulin heavy chain-binding protein
  • endoplasmic reticulum lumenal Ca(2+)-binding protein grp78
  • glucose-regulated protein, 78kDa
  • XAP-1 antigen
  • glucose regulated protein, 78 kDa
  • heat shock 70kD protein 5 (glucose-regulated protein, 78kD)
  • heat shock 70kD protein 5
  • heat shock 70kDa protein 5 (glucose-regulated protein)
  • steroidogenesis-activator polypeptide
  • bip
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