GRM7 蛋白
(Glutamate Receptor, Metabotropic 7 (GRM7))
L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].
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Popular GRM7 蛋白
Aliases for GRM7 蛋白
glutamate metabotropic receptor 7 (GRM7) 蛋白glutamate receptor, metabotropic 7 (Grm7) 蛋白
glutamate metabotropic receptor 7 (Grm7) 蛋白
6330570A01Rik 蛋白
BB176677 蛋白
C030018L03 蛋白
E130018M02Rik 蛋白
GLUR7 蛋白
Gpr1g 蛋白
GPRC1G 蛋白
Gprc1g 蛋白
MGLU7 蛋白
MGLUR7 蛋白
mGluR7 蛋白
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