GRM2 蛋白
(Glutamate Receptor, Metabotropic 2 (GRM2))
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
GRM2 蛋白 by Origin
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GRM2 蛋白 by Source
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GRM2 蛋白 by 蛋白类型
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GRM2 蛋白 by 应用范围
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Popular GRM2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355778
Quantity
10 μg
Datasheet
Datasheet
Aliases for GRM2 蛋白
glutamate metabotropic receptor 2 (GRM2) 蛋白glutamate receptor, metabotropic 2 (Grm2) 蛋白
glutamate metabotropic receptor 2 (Grm2) 蛋白
4930441L02Rik 蛋白
GLUR2 蛋白
GPRC1B 蛋白
Gprc1b 蛋白
mGlu2 蛋白
MGLUR2 蛋白
mGluR2 蛋白
mGluR7 蛋白
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