GRM2 抗体
(Glutamate Receptor, Metabotropic 2 (GRM2))
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
recommended
GRM2 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, Hamster, Bat, Pig WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
recommended
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Popular GRM2 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5611158
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Hamster, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN1048929
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Monkey, Rabbit
Application
IHC, IHC (p)
Validations
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Cat. No.
ABIN213522
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC, LCI
Validations
- (4)
Cat. No.
ABIN7043247
Quantity
25 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (2)
Cat. No.
ABIN7159436
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Dog, Hamster, Human, Rabbit, Rat
Application
IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1048928
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
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Cat. No.
ABIN571205
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
ELISA, WB, IF (p), IHC (p), IF (cc), ICC, IHC (fro)
Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN6242365
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC
Validations
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Cat. No.
ABIN7248053
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
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Cat. No.
ABIN561141
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF
Validations
- (1)
Cat. No.
ABIN516203
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
- (1)
Cat. No.
ABIN516204
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN1535755
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Human, Mouse, Rat
Application
IF (p), IHC (p)
Validations
Cat. No.
ABIN1386756
Quantity
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Datasheet
Datasheet
Latest Publications for our GRM2 抗体
: "Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 1, pp. 103-13, (2009) (PubMed).: "Glial proliferation and metabotropic glutamate receptor expression in amyotrophic lateral sclerosis." in: Journal of neuropathology and experimental neurology, Vol. 63, Issue 8, pp. 831-40, (2004) (PubMed).
: "The metabotropic glutamate receptor 5 is necessary for late-phase long-term potentiation in the hippocampal CA1 region." in: Brain research, Vol. 1022, Issue 1-2, pp. 12-8, (2004) (PubMed).
: "Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 40, pp. 8752-61, (2004) (PubMed).
: "Control of kinetic properties of GluR2 flop AMPA-type channels: impact of R/G nuclear editing." in: The European journal of neuroscience, Vol. 15, Issue 1, pp. 51-62, (2002) (PubMed).
: "Presynaptic group II metabotropic glutamate receptors reduce stimulated and spontaneous transmitter release in human dentate gyrus." in: Neuropharmacology, Vol. 42, Issue 3, pp. 297-305, (2002) (PubMed).
: "Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses." in: Nature, Vol. 410, Issue 6828, pp. 588-92, (2001) (PubMed).
Aliases for GRM2 抗体
glutamate metabotropic receptor 2 (GRM2) 抗体glutamate receptor, metabotropic 2 (Grm2) 抗体
glutamate metabotropic receptor 2 (Grm2) 抗体
4930441L02Rik 抗体
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