GRK2 抗体
(Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008].
recommended
recommended
KO Validated ADRBK1 适用: 人 WB, IHC (p), IF, ICC, FACS, IP 宿主: 兔 Polyclonal unconjugated
recommended
GRK2 抗体 by Grade
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GRK2 抗体 by 适用
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Popular GRK2 抗体
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Reactivity
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Validations
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Datasheet
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Application
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Quantity
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Datasheet
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WB, IHC (p), IF, ICC, FACS, IP
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Cat. No.
ABIN2855125
Quantity
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Cat. No.
ABIN969178
Quantity
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WB, ELISA, IHC, IF, ICC
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Cat. No.
ABIN6259807
Quantity
100 μL
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Cat. No.
ABIN1882061
Quantity
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WB, ELISA, IHC
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Cat. No.
ABIN7184989
Quantity
100 μg
Datasheet
Datasheet
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Cat. No.
ABIN7184410
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN7145433
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
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WB, ELISA
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Cat. No.
ABIN3184941
Quantity
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Datasheet
Datasheet
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WB, ELISA, IHC
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Cat. No.
ABIN3184940
Quantity
100 μL
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Datasheet
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Cat. No.
ABIN185583
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Application
WB
Validations
- (3)
Cat. No.
ABIN2784714
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Mouse, Pig, Rat
Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7294874
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN6655844
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
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Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GRK2 抗体
: "Alteration of β-Adrenoceptor Signaling in Left Ventricle of Acute Phase Takotsubo Syndrome: a Human Study." in: Scientific reports, Vol. 8, Issue 1, pp. 12731, (2018) (PubMed).: "GRK2 activation by receptors: role of the kinase large lobe and carboxyl-terminal tail." in: Biochemistry, Vol. 48, Issue 20, pp. 4285-93, (2009) (PubMed).
: "Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 6, pp. 851-60, (2009) (PubMed).
: "EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation." in: Molecular biology of the cell, Vol. 19, Issue 7, pp. 2973-83, (2008) (PubMed).
: "Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure." in: European heart journal, Vol. 26, Issue 17, pp. 1752-8, (2005) (PubMed).
: "The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8052-7, (2003) (PubMed).
: "Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 30219-26, (2003) (PubMed).
: "The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and G-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated ..." in: The Journal of biological chemistry, Vol. 278, Issue 20, pp. 18658-63, (2003) (PubMed).
: "Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinase." in: World journal of gastroenterology : WJG, Vol. 9, Issue 4, pp. 800-3, (2003) (PubMed).
: "Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells." in: Anesthesiology, Vol. 98, Issue 2, pp. 343-8, (2003) (PubMed).
Aliases for GRK2 抗体
beta-adrenergic receptor kinase 1 (Tsp_00497) 抗体G protein-coupled receptor kinase 2 (grk2) 抗体
G protein-coupled receptor kinase 2 (Grk2) 抗体
G protein-coupled receptor kinase 2 (GRK2) 抗体
Adrbk-1 抗体
Bark-1 抗体
BARK1 抗体
BETA-ARK1 抗体
betaARK1 抗体
GRK-2 抗体
GRK2 抗体
Grk2 抗体
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