GRIN1/NMDAR1 产品
(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
Categories
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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Featured GRIN1/NMDAR1 Categories
GRIN1/NMDAR1 抗体
High quality antibodies with extensive validation data.
GRIN1/NMDAR1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
GRIN1/NMDAR1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GRIN1/NMDAR1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IF
Validations
- (5)
Cat. No.
ABIN185678
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (4)
Cat. No.
ABIN6141400
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6263664
Quantity
100 μL
Datasheet
Datasheet
Recommended GRIN1/NMDAR1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967062
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967061
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967060
Quantity
96 tests
Datasheet
Datasheet
Recommended GRIN1/NMDAR1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355746
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398170
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7502540
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GRIN1/NMDAR1 Products
: "Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities." in: Disease models & mechanisms, Vol. 12, Issue 2, (2019) (PubMed).: "Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons." in: JCI insight, Vol. 5, (2019) (PubMed).
: "Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. ..." in: Nature medicine, Vol. 24, Issue 3, pp. 313-325, (2018) (PubMed).
: "2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor." in: Journal of cellular physiology, (2017) (PubMed).
: "Pharmacological inhibition of PTEN attenuates cognitive deficits caused by neonatal repeated exposures to isoflurane via inhibition of NR2B-mediated tau phosphorylation in rats." in: Neuropharmacology, Vol. 114, pp. 135-145, (2017) (PubMed).
: "Motor neuron degeneration following glycine-mediated excitotoxicity induces spastic paralysis after spinal cord ischemia/reperfusion injury in rabbit." in: American journal of translational research, Vol. 9, Issue 7, pp. 3411-3421, (2017) (PubMed).
: "Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons: OPPOSING ROLES FOR THE TRANSCRIPTION FACTORS CREB (cAMP RESPONSE ELEMENT BINDING) PROTEIN AND Sp1 ..." in: The Journal of biological chemistry, Vol. 291, Issue 53, pp. 27279-27288, (2016) (PubMed).
: "Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injury-induced coma: orexin-A-mediated N-methyl-D-aspartate receptor subunit NR1 upregulation." in: Neural regeneration research, Vol. 11, Issue 6, pp. 951-6, (2016) (PubMed).
: "Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's disease." in: Neurobiology of disease, Vol. 74, pp. 254-62, (2015) (PubMed).
: "Conantokin-G attenuates detrimental effects of NMDAR hyperactivity in an ischemic rat model of stroke." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122840, (2015) (PubMed).
Synonyms and alternative names related to GRIN1/NMDAR1
glutamate ionotropic receptor NMDA type subunit 1 (GRIN1), glutamate receptor, ionotropic, N-methyl D-aspartate 1 S homeolog (grin1.S), glutamate ionotropic receptor NMDA type subunit 1 (grin1), glutamate ionotropic receptor NMDA type subunit 1 (Grin1), NMDA receptor 1 (Nmdar1), G protein-regulated inducer of neurite outgrowth 1 (Gprin1), glutamate receptor, ionotropic, NMDA1 (zeta 1) (Grin1), glutamate receptor, ionotropic, N-methyl D-aspartate 1a (grin1a), GB19253, GluN1, GluRdelta1, GluRzeta1, GRIN1, M100174, MRD8, NMD-R1, NMDA1, nmda1, Nmdar, NMDAR1, nmdar1, NMDAR1.1, NR1, Rgsc174, Z16, zgc:152678Protein level used designations for GRIN1/NMDAR1
- N-methyl-D-aspartate receptor channel, subunit zeta-1
- N-methyl-D-aspartate receptor subunit NR1
- NMD-R1
- glutamate [NMDA] receptor subunit zeta 1
- glutamate [NMDA] receptor subunit zeta-1
- glutamate receptor ionotropic, NMDA 1
- N-methyl-D-aspartate receptor
- NMDA glutamate receptor
- glutamate receptor, ionotropic, N-methyl D-aspartate 1
- N-methyl-D-aspartate glutamate receptor
- NMDA R1 receptor C1 cassette
- neurotransmitter receptor
- NMDA-type glutamate receptor 1
- NMDA-type glutamate receptor subunit 1
- N-methyl-D-aspartate receptor 1
- Glutamate [NMDA] receptor subunit zeta-1
- glutamate receptor subunit zeta 1
- N-methyl-D-aspartate receptor type 1
- NMDA receptor glycine-binding subunit NR1.1
- glutamate receptor, ionotropic, N-methyl D-aspartate 1a
- round spermatid basic protein 1
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