GRIK2 产品
(Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))
Categories
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008].
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Featured GRIK2 Categories
GRIK2 抗体
High quality antibodies with extensive validation data.
GRIK2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
GRIK2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GRIK2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN7267415
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN3022675
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS, Neut
Validations
- (3)
Cat. No.
ABIN5611208
Quantity
100 μL
Datasheet
Datasheet
Recommended GRIK2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN776955
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rabbit
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN774999
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Quantitative
Validations
Cat. No.
ABIN778939
Quantity
96 tests
Datasheet
Datasheet
Recommended GRIK2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355738
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418479
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2722000
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our GRIK2 Products
: "Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish." in: Frontiers in cell and developmental biology, Vol. 6, pp. 114, (2018) (PubMed).: "Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid." in: Journal of the American Society of Nephrology : JASN, Vol. 25, Issue 6, pp. 1187-97, (2014) (PubMed).
: "Novel application of stem cell-derived neurons to evaluate the time- and dose-dependent progression of excitotoxic injury." in: PLoS ONE, Vol. 8, Issue 5, pp. e64423, (2013) (PubMed).
: "A defect in the ionotropic glutamate receptor 6 gene (GRIK2) is associated with autosomal recessive mental retardation." in: American journal of human genetics, Vol. 81, Issue 4, pp. 792-8, (2007) (PubMed).
: "Kainate receptors." in: Cell and tissue research, Vol. 326, Issue 2, pp. 457-82, (2006) (PubMed).
: "Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder." in: Neuroreport, Vol. 15, Issue 4, pp. 699-702, (2004) (PubMed).
: "Functions of glutamate transporters in the brain." in: Neuroscience research, Vol. 37, Issue 1, pp. 15-9, (2000) (PubMed).
: "Human GluR6 kainate receptor (GRIK2): molecular cloning, expression, polymorphism, and chromosomal assignment." in: Genomics, Vol. 20, Issue 3, pp. 435-40, (1994) (PubMed).
Synonyms and alternative names related to GRIK2
glutamate ionotropic receptor kainate type subunit 2 (GRIK2), glutamate receptor, ionotropic, kainate 2 L homeolog (grik2.L), glutamate receptor, ionotropic, kainate 2 (grik2), glutamate ionotropic receptor kainate type subunit 2 (Grik2), glutamate receptor, ionotropic, kainate 2 (beta 2) (Grik2), AW124492, eaa4, EAA4, glr6, GLR6, GluK2, gluk6, GLUK6, Glur-6, glur6, GluR6, GLUR6, Glur6, Glurbeta2, grik2, GRIK2, grik2-A, GRIK5, mrt6, MRT6Protein level used designations for GRIK2
- glutamate receptor 6
- glutamate receptor, ionotropic kainate 2
- glutamate receptor, ionotropic, kainate 5
- bA487F5.1
- excitatory amino acid receptor 4
- gluR-6
- glutamate receptor form A
- glutamate receptor form B
- glutamate receptor form C
- glutamate receptor form D
- glutamate receptor form E
- glutamate receptor ionotropic, kainate 2
- gluR beta-2
- glutamate receptor beta-2
- glutamate receptor, ionotropic, kainate 2
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