GRIA2 抗体
(Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG\; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008].
recommended
recommended
GRIA2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7A7A3 unconjugated
recommended
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Popular GRIA2 抗体
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Reactivity
Application
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Cat. No.
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Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Reactivity
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Application
IHC, ELISA, FACS
Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Cat. No.
ABIN3031067
Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
ABIN7427138
Quantity
100 μL
Datasheet
Datasheet
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Application
WB, IHC, ELISA, IHC (p)
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Cat. No.
ABIN351533
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p)
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Cat. No.
ABIN3043838
Quantity
100 μg
Datasheet
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WB, IHC
Validations
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Cat. No.
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Quantity
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Cat. No.
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Reactivity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
100 μL
Datasheet
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Reactivity
Chicken, Human, Monkey, Mouse, Rat, Zebrafish (Danio rerio)
Application
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Validations
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Quantity
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Datasheet
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Latest Publications for our GRIA2 抗体
: "Modulation of synaptic plasticity, motor unit physiology, and TDP-43 pathology by CHCHD10." in: Acta neuropathologica communications, Vol. 10, Issue 1, pp. 95, (2022) (PubMed).: "Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 2, pp. 346-351, (2018) (PubMed).
: "Dcf1 Triggers Dendritic Spine Formation and Facilitates Memory Acquisition." in: Molecular neurobiology, Vol. 55, Issue 1, pp. 763-775, (2018) (PubMed).
: "Specific Alterations in Astrocyte Properties via the GluA2-GAPDH Complex Associated with Multiple Sclerosis." in: Scientific reports, Vol. 8, Issue 1, pp. 12856, (2018) (PubMed).
: "The paracrine effect of cobalt chloride on BMSCs during cognitive function rescue in the HIBD rat." in: Behavioural brain research, Vol. 332, pp. 99-109, (2017) (PubMed).
: "Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development." in: Scientific reports, Vol. 6, pp. 35456, (2016) (PubMed).
: "Disrupting GluA2-GAPDH Interaction Affects Axon and Dendrite Development." in: Scientific reports, Vol. 6, pp. 30458, (2016) (PubMed).
: "Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo." in: Brain structure & function, Vol. 220, Issue 1, pp. 47-58, (2015) (PubMed).
: "TRPC3 channels critically regulate hippocampal excitability and contextual fear memory." in: Behavioural brain research, Vol. 281, pp. 69-77, (2015) (PubMed).
: "Development- and age-related alterations in the expression of AMPA receptor subunit GluR2 and its trafficking proteins in the hippocampus of male mouse brain." in: Biogerontology, Vol. 16, Issue 3, pp. 317-28, (2015) (PubMed).
Aliases for GRIA2 抗体
glutamate ionotropic receptor AMPA type subunit 2 (GRIA2) 抗体glutamate receptor, ionotropic, AMPA 2 (GRIA2) 抗体
glutamate receptor, ionotropic, AMPA2 (alpha 2) (Gria2) 抗体
glutamate ionotropic receptor AMPA type subunit 2 (Gria2) 抗体
glutamate receptor, ionotropic, AMPA 2a (gria2a) 抗体
glutamate receptor, ionotropic, AMPA 2 S homeolog (gria2.S) 抗体
GluA2 抗体
GluR-2 抗体
Glur-2 抗体
GluR-B 抗体
gluR-B 抗体
GluR-K2 抗体
GLUR2 抗体
Glur2 抗体
GluR2 抗体
glur2 抗体
glur2a 抗体
GLURB 抗体
gria2.1 抗体
HBGR2 抗体
zfGRIA2[a] 抗体
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