GREM1 抗体
(Gremlin 1 (GREM1))
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
recommended
GREM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
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Find available monoclonal or polyclonal GREM1 抗体. Click on a link to go to the corresponding products.
GREM1 抗体 by 克隆
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Popular GREM1 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (5)
Cat. No.
ABIN687082
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN390078
Quantity
400 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
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Cat. No.
ABIN7434692
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7434695
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7426475
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7442135
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN565294
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
IHC, ELISA
Validations
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Cat. No.
ABIN7154448
Quantity
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Datasheet
Datasheet
Reactivity
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Cat. No.
ABIN7437098
Quantity
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Cat. No.
ABIN565289
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN6750392
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Goat, Guinea Pig, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
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Validations
- (1)
Cat. No.
ABIN6749873
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Human, Monkey, Pig, Rabbit
Application
IHC, ELISA, IHC (p)
Validations
- (1)
Cat. No.
ABIN208396
Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Quantity
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Datasheet
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Latest Publications for our GREM1 抗体
: "Gremlin is a key pro-fibrogenic factor in chronic pancreatitis." in: Journal of molecular medicine (Berlin, Germany), (2015) (PubMed).: "Tubular overexpression of gremlin induces renal damage susceptibility in mice." in: PLoS ONE, Vol. 9, Issue 7, pp. e101879, (2014) (PubMed).
: "Overexpression of Gremlin-1 in patients with Loeys-Dietz syndrome: implications on pathophysiology and early disease detection." in: PLoS ONE, Vol. 9, Issue 8, pp. e104742, (2014) (PubMed).
: "Identification of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma." in: Oncology reports, Vol. 30, Issue 2, pp. 968-78, (2013) (PubMed).
: "Molecular differentiation between osteophytic and articular cartilage--clues for a transient and permanent chondrocyte phenotype." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 20, Issue 2, pp. 162-71, (2012) (PubMed).
: "Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 24, Issue 4, pp. 1121-9, (2009) (PubMed).
: "Elevated levels of gremlin-1 in eutopic endometrium and peripheral serum in patients with endometriosis." in: Fertility and sterility, Vol. 91, Issue 2, pp. 350-8, (2009) (PubMed).
: "Gremlin: a novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy." in: Transplantation proceedings, Vol. 40, Issue 3, pp. 734-9, (2008) (PubMed).
: "A gain-of-function mutation in the PDGFR-beta alters the kinetics of injury response in liver and skin." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 88, Issue 11, pp. 1204-14, (2008) (PubMed).
: "Thy-1 is expressed in myofibroblasts but not found in hepatic stellate cells following liver injury." in: Histochemistry and cell biology, Vol. 131, Issue 1, pp. 115-27, (2008) (PubMed).
Aliases for GREM1 抗体
gremlin 1a, DAN family BMP antagonist (grem1a) 抗体gremlin 1, DAN family BMP antagonist (GREM1) 抗体
gremlin 1 (LOC662541) 抗体
gremlin 1, DAN family BMP antagonist (grem1) 抗体
gremlin 1, DAN family BMP antagonist (Grem1) 抗体
gremlin 1, DAN family BMP antagonist L homeolog (grem1.L) 抗体
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