GPR77 产品
(G Protein-Coupled Receptor 77 (GPR77))
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This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].
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Featured GPR77 Categories
GPR77 抗体
High quality antibodies with extensive validation data.
GPR77 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
GPR77 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GPR77 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7139743
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1048365
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN525897
Quantity
50 μg
Datasheet
Datasheet
Recommended GPR77 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1124566
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1124567
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1124568
Quantity
96 tests
Datasheet
Datasheet
Recommended GPR77 蛋白
Latest Publications for our GPR77 Products
: "T Cell Expression of C5a Receptor 2 Augments Murine Regulatory T Cell (TREG) Generation and TREG-Dependent Cardiac Allograft Survival." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2186-2198, (2018) (PubMed).: "Monitoring C5aR2 Expression Using a Floxed tdTomato-C5aR2 Knock-In Mouse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 9, pp. 3234-3248, (2017) (PubMed).
: "C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment." in: Immunology and cell biology, Vol. 92, Issue 7, pp. 631-9, (2014) (PubMed).
: "Relationship of C5L2 receptor to skeletal muscle substrate utilization." in: PLoS ONE, Vol. 8, Issue 2, pp. e57494, (2013) (PubMed).
: "The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7633-44, (2010) (PubMed).
Synonyms and alternative names related to GPR77
complement component 5a receptor 2 (C5AR2), complement component 5a receptor 2 (C5ar2), C5L2, E030029A11Rik, GPF77, GPR77, Gpr77Protein level used designations for GPR77
- G protein-coupled receptor 77
- G protein-coupled receptor C5L2
- C5a anaphylatoxin chemotactic receptor 2
- C5a anaphylatoxin chemotactic receptor C5L2
- G-protein coupled receptor 77
- C5A receptor beta
- complement 5A receptor beta
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