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GPR39 产品

(G Protein-Coupled Receptor 39 (GPR39))

Categories

Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).

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Featured GPR39 Categories

GPR39 抗体

High quality antibodies with extensive validation data.

GPR39 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GPR39 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Horse, Human, Mouse, Rabbit, Rat
Application IHC, IHC (p)
Validations
  • (2)
  • (4)
Cat. No. ABIN1048812
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (4)
Cat. No. ABIN7043159
Quantity 25 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7153343
Quantity 100 μg
Datasheet Datasheet

Recommended GPR39 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1779176
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421155
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1330157
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GPR39 Products

Alkayed, Cao, Qian, Nagarajan, Liu, Nelson, Xie, Li, Fan, Liu, Grafe, Davis, Xiao, Barnes, Kaul: "Control of Coronary Vascular Resistance by Eicosanoids via a Novel GPCR." in: , (2022) (PubMed).

Davis, Bah, Zhang, Nelson, Golgotiu, Nie, Alkayed, Young, Woltjer, Silbert, Grafe, Alkayed: "GPR39 localization in the aging human brain and correlation of expression and polymorphism with vascular cognitive impairment." in: Alzheimer's & dementia (New York, N. Y.), Vol. 7, Issue 1, pp. e12214, (2021) (PubMed).

Yang, Li, Zhang, Chen: "Zac1/GPR39 phosphorylating CaMK-II contributes to the distinct roles of Pax3 and Pax7 in myogenic progression." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1864, Issue 2, pp. 407-419, (2018) (PubMed).

Kolodziejski, Pruszynska-Oszmalek, Sassek, Kaczmarek, Szczepankiewicz, Billert, Mackowiak, Strowski, Nowak: "Changes in obestatin gene and GPR39 receptor expression in peripheral tissues of rat models of obesity, type 1 and type 2 diabetes." in: Journal of diabetes, Vol. 9, Issue 4, pp. 353-361, (2017) (PubMed).

Qiao, Zhao, Zhang, Peng, Chen, Zhang, Zheng, Jin, Ni, Duan, Guo: "GPR39 is region-specifically expressed in mouse oviduct correlating with the Zn(2+) distribution." in: Theriogenology, Vol. 88, pp. 98-105, (2016) (PubMed).

Zhao, Qiao, Zhang, Zhang, Lei, Wang, Deng, Ning, Cao, Guo, Liu, Duan: "GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing." in: Scientific reports, Vol. 5, pp. 7913, (2015) (PubMed).

Cohen, Asraf, Sekler, Hershfinkel: "Extracellular pH regulates zinc signaling via an Asp residue of the zinc-sensing receptor (ZnR/GPR39)." in: The Journal of biological chemistry, Vol. 287, Issue 40, pp. 33339-50, (2012) (PubMed).

Deans, Singh, Gibson, Elisseeff: "Regulating synthetic gene networks in 3D materials." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 38, pp. 15217-22, (2012) (PubMed).

Besser, Chorin, Sekler, Silverman, Atkin, Russell, Hershfinkel: "Synaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 9, pp. 2890-901, (2009) (PubMed).

Holst, Holliday, Bach, Elling, Cox, Schwartz: "Common structural basis for constitutive activity of the ghrelin receptor family." in: The Journal of biological chemistry, Vol. 279, Issue 51, pp. 53806-17, (2004) (PubMed).

Synonyms and alternative names related to GPR39

G protein-coupled receptor 39 (Gpr39), G protein-coupled receptor 39 (GPR39), G-protein coupled receptor 39 (LOC720610), G protein-coupled receptor 39 (gpr39), 4933415E13Rik, GPR39, zgc:64187

Protein level used designations for GPR39

  • G-protein coupled receptor 39
  • G protein-coupled receptor 39
  • G-protein coupled receptor 39-1
  • G-protein coupled receptor 39-like
  • orphan G-protein coupled receptor 39
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