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GNRH1 产品

(Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))

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The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012].

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Featured GNRH1 Categories

GNRH1 抗体

High quality antibodies with extensive validation data.

GNRH1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GNRH1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GNRH1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (7)
Cat. No. ABIN7429916
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IP, ICC
Validations
  • (3)
Cat. No. ABIN7429913
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN6141257
Quantity 100 μL
Datasheet Datasheet

Recommended GNRH1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6963398
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (6)
  • (1)
Cat. No. ABIN6956287
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967184
Quantity 96 tests
Datasheet Datasheet

Recommended GNRH1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355442
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355444
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392371
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GNRH1 Products

Jin, Hou, Meng, Ma, Wang, Liu, Sha, Ding, Han: "Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice." in: Ecotoxicology and environmental safety, Vol. 208, pp. 111748, (2021) (PubMed).

Tang, Liu, Peng, Ju, Hao, Peng, Chen: "Nectin-like molecule 2, a necessary sexual maturation regulator, participates in congenital hypogonadotropic hypogonadism." in: Gene, Vol. 754, pp. 144885, (2020) (PubMed).

Huang, Zhu, Li, Wang, Li, Yang, Zheng, Liu, Zhang, Zhang, Liu: "Cadmium exposure during prenatal development causes testosterone disruption in multigeneration via SF-1 signaling in rats." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 135, pp. 110897, (2020) (PubMed).

Zhang, Meng, Chen, Zhang, Zhang, Tian, Wang, Yu, Zhou, Diao: "Perfluorooctanoic acid exposure impact a trade-off between self-maintenance and reproduction in lizards (Eremias argus) in a gender-dependent manner." in: Environmental pollution (Barking, Essex : 1987), Vol. 262, pp. 114341, (2020) (PubMed).

Olayaki, Alagbonsi, Abdulrahim, Adeyemi, Bakare, Omeiza: "Melatonin prevents and ameliorates lead-induced gonadotoxicity through antioxidative and hormonal mechanisms." in: Toxicology and industrial health, Vol. 34, Issue 9, pp. 596-608, (2019) (PubMed).

Ye, Li, Zhang, Ma, Ji, Huang, Curry, Liu, Liu: "Pyrethroid Insecticide Cypermethrin Accelerates Pubertal Onset in Male Mice via Disrupting Hypothalamic-Pituitary-Gonadal Axis." in: Environmental science & technology, Vol. 51, Issue 17, pp. 10212-10221, (2018) (PubMed).

Ciechanowska, Łapot, Paruszewska, Radawiec, Przekop et al.: "The influence of dopaminergic system inhibition on biosynthesis of gonadotrophin-releasing hormone (GnRH) and GnRH receptor in anoestrous sheep; hierarchical role of kisspeptin and RFamide-related ..." in: Reproduction, fertility, and development, (2018) (PubMed).

Pandolfi, Hoffmann, Schoeller, Gorman, Mellon: "Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Development, and Impairs Female Fertility Through Disrupted GnRH Neuron Migration." in: Molecular neurobiology, Vol. 55, Issue 11, pp. 8709-8727, (2018) (PubMed).

Poliandri, Miller, Howard, Nobles, Ruiz-Babot, Harmer, Tinker, McKay, Guasti, Dunkel: "Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells." in: Molecular and cellular endocrinology, Vol. 447, pp. 12-22, (2017) (PubMed).

Hoffmann, Trang, Gong, Kimura, Pandolfi, Mellon: "Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 36, Issue 12, pp. 3506-18, (2016) (PubMed).

Synonyms and alternative names related to GNRH1

gonadotropin releasing hormone 1 (GNRH1), gonadotropin releasing hormone 1 (Gnrh1), gonadotropin releasing hormone 1 L homeolog (gnrh1.L), prepro-gonadotropin-releasing hormone (gnrh1), CGNRH-I, GNRH, Gnrh, GnRH, gnrh, GnRH-I, gnrh1, Gnrh2, Gnrha, GRH, grh, HH12, hpg, LHRH, Lhrh, lhrh, Lhrh1, LNRH, Lnrh, lnrh, mdGnRH, mdgnrh, mfGnRH, Rgnrhg1

Protein level used designations for GNRH1

  • GnRH-associated peptide 1
  • gonadotropin-releasing hormone 1 (leutinizing-releasing hormone)
  • luliberin I
  • progonadoliberin I
  • progonadoliberin-1
  • prolactin release-inhibiting factor
  • gonadotropin releasing hormone 2
  • hypogonadal
  • luteinizing hormone-releasing hormone I
  • gonadotropin releasing hormone 1
  • luteinizing hormone-releasing hormone
  • chicken gonadotrophin releasing hormone-I
  • gonadotrophin-releasing hormone I
  • gonadotropin-releasing hormone associated peptide
  • progonadoliberin-1 preproprotein
  • Progonadoliberin I
  • Progonadoliberin-1
  • luliberin i
  • luteinizing hormone
  • luteinizing-releasing hormone
  • Medaka-type gonadotropin-releasing hormone
  • gonadotropin-releasing hormone
  • medaka-type gonadotropin-releasing hormone
  • mfGnRH
  • gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
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