GNAQ 产品
(Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))
Categories
This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010].
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Featured GNAQ Categories
Recommended GNAQ 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (6)
Cat. No.
ABIN2855848
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN516106
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN763181
Quantity
100 μL
Datasheet
Datasheet
Recommended GNAQ 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123242
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355347
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355345
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our GNAQ Products
: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." in: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).: "Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9513-25, (2016) (PubMed).
: "Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation." in: BMC immunology, Vol. 10, pp. 27, (2009) (PubMed).
: "Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly." in: FEBS letters, Vol. 531, Issue 3, pp. 565-9, (2002) (PubMed).
: "Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 13254-9, (2002) (PubMed).
: "G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 23, pp. 9113-7, (1991) (PubMed).
Synonyms and alternative names related to GNAQ
guanine nucleotide binding protein (G protein), q polypeptide (gnaq), G protein subunit alpha q (GNAQ), G protein subunit alpha q (Gnaq), guanine nucleotide binding protein (G protein), q polypeptide S homeolog (gnaq.S), guanine nucleotide binding protein, alpha q polypeptide (Gnaq), 1110005L02Rik, 6230401I02Rik, AA408290, AW060788, CMC1, Dsk1, Dsk10, G-ALPHA-q, g-alpha-q, Galphaq, GAQ, gaq, Gnaq, gnaqb, Gq, GqI, si:ch73-270f14.2, SWSProtein level used designations for GNAQ
- Galpha q
- gnaqa
- guanine nucleotide-binding protein G(q) subunit alpha
- guanine nucleotide-binding protein alpha-q
- G alpha q
- guanine nucleotide binding protein alpha q subunit
- guanine nucleotide binding protein, alpha q polypeptide
- guanine nucleotide regulatory protein G alpha q
- heterotrimeric guanine nucleotide-binding protein alpha q subunit
- guanine nucleotide-binding protein G(q) alpha subunit
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