Glycocalicin 产品
(Glycocalicin (GC))
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Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010].
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Recommended Glycocalicin 抗体
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Reactivity
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Application
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ABIN7437521
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Recommended Glycocalicin ELISA试剂盒
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ABIN6956247
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Recommended Glycocalicin 蛋白
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ABIN7402409
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Datasheet
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Latest Publications for our Glycocalicin Products
: "iTRAQ-Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism." in: Proteomics. Clinical applications, Vol. 12, Issue 3, pp. e1700085, (2019) (PubMed).: "Factors associated with the platelet count in patients with chronic hepatitis C." in: Thrombosis research, Vol. 135, Issue 5, pp. 823-8, (2015) (PubMed).
: "A factor VIII-derived peptide enables von Willebrand factor (VWF)-binding of artificial platelet nanoconstructs without interfering with VWF-adhesion of natural platelets." in: Nanoscale, Vol. 6, Issue 9, pp. 4765-73, (2014) (PubMed).
Synonyms and alternative names related to Glycocalicin
glycoprotein Ib platelet alpha subunit (GP1BA), glucagon (GCG), BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GLP1, GLP2, GP1B, GPIbA, GRPP, VWDPProtein level used designations for Glycocalicin
- GP-Ib alpha
- antigen CD42b-alpha
- platelet glycoprotein Ib alpha chain
- platelet membrane glycoprotein 1b-alpha subunit
- glicentin-related polypeptide
- glucagon-like peptide 1
- glucagon-like peptide 2
- preproglucagon
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