Glucocorticoid Receptor 产品
(Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
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This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011].
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Featured Glucocorticoid Receptor Categories
Glucocorticoid Receptor 抗体
High quality antibodies with extensive validation data.
Glucocorticoid Receptor ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Glucocorticoid Receptor 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Glucocorticoid Receptor 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
- (6)
Cat. No.
ABIN3023091
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (6)
Cat. No.
ABIN561138
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP, IHC (p), ICC
Validations
- (2)
- (5)
Cat. No.
ABIN2854939
Quantity
100 μL
Datasheet
Datasheet
Recommended Glucocorticoid Receptor ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6720464
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958262
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969020
Quantity
96 tests
Datasheet
Datasheet
Recommended Glucocorticoid Receptor 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312973
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312972
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7421104
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Glucocorticoid Receptor Products
: "Early weaning leads to specific glucocorticoid signalling in fat depots of adult rats." in: Endocrine, Vol. 67, Issue 1, pp. 180-189, (2020) (PubMed).: "Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells." in: Molecular biology reports, Vol. 47, Issue 2, pp. 1021-1032, (2020) (PubMed).
: "Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus." in: Cell reports, Vol. 26, Issue 13, pp. 3629-3642.e4, (2019) (PubMed).
: "Chronic Gestational Inflammation: Transfer of Maternal Adaptation over Two Generations of Progeny." in: Mediators of inflammation, Vol. 2019, pp. 9160941, (2019) (PubMed).
: "Decreased H3K9ac level of StAR mediated testicular dysplasia induced by prenatal dexamethasone exposure in male offspring rats." in: Toxicology, Vol. 408, pp. 1-10, (2018) (PubMed).
: "Androgen receptor reverts dexamethasone‑induced inhibition of prostate cancer cell proliferation and migration." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5887-5893, (2018) (PubMed).
: "Inhibitory Effects of Prunella vulgaris L. Extract on 11β-HSD1 in Human Skin Cells." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 1762478, (2018) (PubMed).
: "Endoplasmic Reticulum Stress PERK-ATF4-CHOP Pathway Is Associated with Hypothalamic Neuronal Injury in Different Durations of Stress in Rats." in: Frontiers in neuroscience, Vol. 11, pp. 152, (2017) (PubMed).
: "Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness." in: Scientific reports, Vol. 7, Issue 1, pp. 6816, (2017) (PubMed).
: "Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels." in: The Journal of clinical investigation, Vol. 126, Issue 11, pp. 4319-4330, (2016) (PubMed).
Synonyms and alternative names related to Glucocorticoid Receptor
nuclear receptor subfamily 3 group C member 1 (NR3C1), nuclear receptor subfamily 3 group C member 1 (nr3c1), nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (nr3c1), nuclear receptor subfamily 3, group C, member 1 (NR3C1), glucocorticoid receptor (LOC100302444), nuclear receptor subfamily 3, group C, member 1 (Nr3c1), nuclear receptor subfamily 3 group C member 1 (Nr3c1), nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), gccr, GCCR, GCL, gcr, Gcr, GCR, GR, gr, GR-A, grl, Grl, GRL, Grl-1, Grl1, LOC100302444, NO, NR3C1, nr3c1, xGR, zgc:113038Protein level used designations for Glucocorticoid Receptor
- glucocorticoid receptor
- nuclear receptor subfamily 3, group C, member 1
- glucocorticoid receptor 1
- GR
- nuclear receptor subfamily 3 group C member 1
- glucocorticoid nuclear receptor variant 1
- glucocorticoid receptor alpha
- glucocorticoid receptor variant P
- glucocorticoid receptor variant beta
- glucocorticoid receptor variant gamma
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