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GLS2 产品

(Glutaminase 2 (Liver, Mitochondrial) (GLS2))

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The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene. [provided by RefSeq, Jul 2008].

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Featured GLS2 Categories

GLS2 抗体

High quality antibodies with extensive validation data.

GLS2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GLS2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GLS2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (6)
Cat. No. ABIN7436594
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC
Validations
  • (2)
  • (4)
Cat. No. ABIN2781319
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN6243842
Quantity 200 μL
Datasheet Datasheet

Recommended GLS2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956184
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1134923
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1134924
Quantity 96 tests
Datasheet Datasheet

Recommended GLS2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355246
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7399565
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2722007
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our GLS2 Products

Wang, Liu, Yao, Li, Yang, Zhang, Chen, Wang: "18F-labeled magnetic nanoparticles for monitoring anti-angiogenic therapeutic effects in breast cancer xenografts." in: Journal of nanobiotechnology, Vol. 17, Issue 1, pp. 105, (2019) (PubMed).

Shroff, Eberlin, Dang, Gouw, Gabay, Adam, Bellovin, Tran, Philbrick, Garcia-Ocana, Casey, Li, Dang, Zare, Felsher: "MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 21, pp. 6539-44, (2015) (PubMed).

Gross, Demo, Dennison, Chen, Chernov-Rogan, Goyal, Janes, Laidig, Lewis, Li, Mackinnon, Parlati, Rodriguez, Shwonek, Sjogren, Stanton, Wang, Yang, Zhao, Bennett: "Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer." in: Molecular cancer therapeutics, Vol. 13, Issue 4, pp. 890-901, (2014) (PubMed).

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Shimmura, Suzuki, Iwata, Tsuchiya, Ohno, Matsuzaki, Iwata, Kameno, Takahashi, Wakuda, Nakamura, Hashimoto, Mori: "Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism." in: Molecular autism, Vol. 4, Issue 1, pp. 6, (2013) (PubMed).

Toriumi, Mouri, Narusawa, Aoyama, Ikawa, Lu, Nagai, Mamiya, Kim, Nabeshima: "Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 6, pp. 1387-96, (2012) (PubMed).

Zacharias, McCullough, Shanmugavelandy, Lee, Lee, Dutta, McHenry, Nguyen, Norton, Jones, Bhattacharya: "Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer." in: Scientific reports, Vol. 7, Issue 1, pp. 16159 (PubMed).

Synonyms and alternative names related to GLS2

glutaminase 2 (glsA2), glutaminase 2 (LOAG_03311), glutaminase 2a (liver, mitochondrial) (gls2a), glutaminase 2 (GLS2), glutaminase 2 (liver, mitochondrial) (Gls2), glutaminase 2 (Gls2), A330074B06Rik, AI195532, GA, Ga, GLS, hLGA, LGA, Lga, si:ch211-216k22.10

Protein level used designations for GLS2

  • glutaminase 2
  • L-glutamine amidohydrolase
  • breast cell glutaminase
  • glutaminase I
  • glutaminase liver isoform, mitochondrial
  • phosphate-activated glutaminase
  • phosphate-dependent glutaminase
  • L-glutaminase
  • liver mitochondrial glutaminase
  • GLS
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