GLRA1 产品
(Glycine Receptor, alpha 1 (GLRA1))
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The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].
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Featured GLRA1 Categories
Recommended GLRA1 抗体
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Reactivity
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7154186
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN516068
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN3017068
Quantity
100 μL
Datasheet
Datasheet
Recommended GLRA1 ELISA试剂盒
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Reactivity
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Cat. No.
Quantity
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Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228771
Quantity
96 tests
Datasheet
Datasheet
Recommended GLRA1 蛋白
Latest Publications for our GLRA1 Products
: "The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABAA receptor isoform in a cell model of hyperekplexia." in: The Journal of biological chemistry, Vol. 295, Issue 1, pp. 138-145, (2020) (PubMed).: "Involvement of glycine receptor α1 subunits in cannabinoid-induced analgesia." in: Neuropharmacology, Vol. 133, pp. 224-232, (2018) (PubMed).
: "Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies." in: JAMA neurology, Vol. 72, Issue 8, pp. 874-81, (2015) (PubMed).
: "Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor." in: The Journal of biological chemistry, Vol. 286, Issue 44, pp. 38814-24, (2011) (PubMed).
: "A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor." in: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 34079-83, (2003) (PubMed).
: "Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits." in: Nature, Vol. 415, Issue 6873, pp. 793-8, (2002) (PubMed).
: "Getting a bead on receptor movements." in: Nature neuroscience, Vol. 4, Issue 3, pp. 219-20, (2001) (PubMed).
Synonyms and alternative names related to GLRA1
glycine receptor alpha 1 (GLRA1), glycine receptor, alpha 1 (Glra1), glycine receptor, alpha 1 (glra1), glycine receptor, alpha 1 subunit (Glra1), B230397M16Rik, GLYRA1, HKPX1, nmf11, oscillator, ot, spasmodic, spd, STHE, [a]Z1Protein level used designations for GLRA1
- glycine receptor, alpha 1 (startle disease/hyperekplexia)
- glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)
- glycine receptor, alpha 1
- glycine receptor subunit alpha-1-like
- glycine receptor 48 kDa subunit
- glycine receptor strychnine-binding subunit
- glycine receptor subunit alpha-1
- glycine receptor, alpha 1 subunit
- GlyR [a]Z1
- glycine receptor subunit alphaZ1
- glycine receptor, alphaZ1 subunit
- glycine receptor alpha 1 subunit
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