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GLRA1 产品

(Glycine Receptor, alpha 1 (GLRA1))

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The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].

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Featured GLRA1 Categories

GLRA1 抗体

High quality antibodies with extensive validation data.

GLRA1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GLRA1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7154186
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN516068
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN3017068
Quantity 100 μL
Datasheet Datasheet

Recommended GLRA1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228771
Quantity 96 tests
Datasheet Datasheet

Recommended GLRA1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355226
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355228
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GLRA1 Products

Zou, Xia, Han, Liu, Xiong: "The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABAA receptor isoform in a cell model of hyperekplexia." in: The Journal of biological chemistry, Vol. 295, Issue 1, pp. 138-145, (2020) (PubMed).

Lu, Fan, Zou, Hou, Pan, Guo, Yao, Du, Homanics, Liu, Zhang, Xiong: "Involvement of glycine receptor α1 subunits in cannabinoid-induced analgesia." in: Neuropharmacology, Vol. 133, pp. 224-232, (2018) (PubMed).

Ariño, Höftberger, Gresa-Arribas, Martínez-Hernández, Armangue, Kruer, Arpa, Domingo, Rojc, Bataller, Saiz, Dalmau, Graus: "Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies." in: JAMA neurology, Vol. 72, Issue 8, pp. 874-81, (2015) (PubMed).

Wang, Lynch: "Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor." in: The Journal of biological chemistry, Vol. 286, Issue 44, pp. 38814-24, (2011) (PubMed).

Schofield, Jenkins, Harrison: "A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor." in: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 34079-83, (2003) (PubMed).

Chatterton, Awobuluyi, Premkumar, Takahashi, Talantova, Shin, Cui, Tu, Sevarino, Nakanishi, Tong, Lipton, Zhang: "Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits." in: Nature, Vol. 415, Issue 6873, pp. 793-8, (2002) (PubMed).

Craig, Lichtman: "Getting a bead on receptor movements." in: Nature neuroscience, Vol. 4, Issue 3, pp. 219-20, (2001) (PubMed).

Synonyms and alternative names related to GLRA1

glycine receptor alpha 1 (GLRA1), glycine receptor, alpha 1 (Glra1), glycine receptor, alpha 1 (glra1), glycine receptor, alpha 1 subunit (Glra1), B230397M16Rik, GLYRA1, HKPX1, nmf11, oscillator, ot, spasmodic, spd, STHE, [a]Z1

Protein level used designations for GLRA1

  • glycine receptor, alpha 1 (startle disease/hyperekplexia)
  • glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)
  • glycine receptor, alpha 1
  • glycine receptor subunit alpha-1-like
  • glycine receptor 48 kDa subunit
  • glycine receptor strychnine-binding subunit
  • glycine receptor subunit alpha-1
  • glycine receptor, alpha 1 subunit
  • GlyR [a]Z1
  • glycine receptor subunit alphaZ1
  • glycine receptor, alphaZ1 subunit
  • glycine receptor alpha 1 subunit
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