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GLI3 产品

(GLI Family Zinc Finger 3 (GLI3))
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008].

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Featured GLI3 Categories

GLI3 抗体

High quality antibodies with extensive validation data.

GLI3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GLI3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GLI3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (8)
  • (1)
Cat. No. ABIN2855813
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, PLA
Validations
  • (4)
Cat. No. ABIN561053
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN129623
Quantity 100 μg
Datasheet Datasheet

Recommended GLI3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385958
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883079
Quantity 96 tests
Datasheet Datasheet

Recommended GLI3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355197
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GLI3 Products

Hehemann, Kalmanek, Choe, Dynda, Hu, Quek, Harrington, Stupp, McVary, Podlasek: "Sonic hedgehog regulation of human rhabdosphincter muscle:Potential implications for treatment of stress urinary incontinence." in: Neurourology and urodynamics, Vol. 37, Issue 8, pp. 2551-2559, (2019) (PubMed).

Jackson, Smith, Amarsaikhan, Han, Neil, Boi, Vrabel, Tolosa, Almada, Fernandez-Zapico, Elsawa: "Modulation of the IL-6 Receptor α Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2908-16, (2015) (PubMed).

Kumari, Chaurasia, Kumar, Dash: "Anti-apoptotic role of sonic hedgehog on blood platelets." in: Thrombosis research, Vol. 134, Issue 6, pp. 1311-5, (2014) (PubMed).

Kanda, Mitsuyasu, Nakao, Kawano, Goto, Matsubara, Nakamura: "Anti-apoptotic role of the sonic hedgehog signaling pathway in the proliferation of ameloblastoma." in: International journal of oncology, Vol. 43, Issue 3, pp. 695-702, (2013) (PubMed).

Haycraft, Banizs, Aydin-Son, Zhang, Michaud, Yoder: "Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function." in: PLoS genetics, Vol. 1, Issue 4, pp. e53, (2005) (PubMed).

Synonyms and alternative names related to GLI3

GLI family zinc finger 3 (GLI3), GLI family zinc finger 3 (Gli3), GLI family zinc finger 3 L homeolog (gli3.L), GLI-Kruppel family member GLI3 (Gli3), GLI family zinc finger 3 (gli3), ACLS, add, AI854843, AU023367, Bph, GCPS, GLI3, GLI3-190, GLI3FL, im:7142603, PAP-A, PAPA, PAPA1, PAPB, Pdn, PHS, PPDIV, xgli3, Xt

Protein level used designations for GLI3

  • GLI-Kruppel family member GLI3
  • glioma-associated oncogene family zinc finger 3
  • oncogene GLI3
  • transcriptional activator GLI3
  • zinc finger protein GLI3
  • GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome)
  • GLI3 full length protein
  • neural specific DNA binding protein
  • neural-specific DNA-binding protein xGLI3
  • xGLI-3
  • GLI-Kruppel family member 3
  • GLI3 form of 190 kDa
  • anterior digit pattern deformity
  • brachyphalangy
  • extra toes
  • polydactyly Nagoya
  • zinc finger transcription factor Gli3
  • GLI family zinc finger 3
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