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GJA8 产品

(Gap Junction Protein, alpha 8, 50kDa (GJA8))

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This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009].

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Featured GJA8 Categories

GJA8 抗体

High quality antibodies with extensive validation data.

GJA8 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GJA8 抗体

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Cat. No. ABIN1774805
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Cat. No. ABIN6744731
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Recommended GJA8 蛋白

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Latest Publications for our GJA8 Products

Ponsaerts, De Vuyst, Retamal, Dhondt, Vermeire, Wang, De Smedt, Zimmermann, Himpens, Vereecke, Leybaert, Bultynck: "Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 11, pp. 4378-95, (2010) (PubMed).

Lin, Liu, Lei, Fan, Liu, Yang, Wang, Liu, Yang: "[A novel GJA8 mutation in a Chinese family with autosomal dominant congenital cataract]." in: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 25, Issue 1, pp. 59-62, (2008) (PubMed).

Shiels, Mackay, Ionides, Berry, Moore, Bhattacharya: "A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant "zonular pulverulent" cataract, on chromosome 1q." in: American journal of human genetics, Vol. 62, Issue 3, pp. 526-32, (1998) (PubMed).

Church, Wang, Steele: "The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping." in: Current eye research, Vol. 14, Issue 10, pp. 979-81, (1996) (PubMed).

Church, Wang, Steele: "The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping." in: Current eye research, Vol. 14, Issue 3, pp. 215-21, (1995) (PubMed).

Synonyms and alternative names related to GJA8

gap junction protein, alpha 8 (Gja8), gap junction protein alpha 8 (GJA8), Aey5, CAE, CAE1, Cnx50, CTRCT1, Cx45.6, Cx50, CX50, CZP1, Lop10, MP70

Protein level used designations for GJA8

  • alpha 8 connexin
  • connexin-50
  • gap junction alpha-8 protein
  • gap junction membrane channel protein alpha 8
  • lens fiber protein MP70
  • lens opacity 10
  • connexin 50
  • cell surface glycoprotein
  • gap junction membrane channel protein alpha-8
  • lens intrinsic membrane protein MP70
  • connexin 45.6
  • connexin-45.6
  • MP38
  • MP64
  • connexin-49
  • cx49
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