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Girdin 产品

(Coiled-Coil Domain Containing 88A (CCDC88A))
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].

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Featured Girdin Categories

Girdin 抗体

High quality antibodies with extensive validation data.

Girdin ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended Girdin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro), ICC
Validations
  • (1)
  • (2)
Cat. No. ABIN755587
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238657
Quantity 200 μL
Datasheet Datasheet
Reactivity Rat
Application IHC, IF
Validations
  • (2)
Cat. No. ABIN7073539
Quantity 100 μL
Datasheet Datasheet

Recommended Girdin ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1134711
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1134712
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our Girdin Products

Ni, Fang, Tong, Tong, Yi, Qiu, Wang, Tong: "Girdin regulates the migration and invasion of glioma cells via the PI3K?Akt signaling pathway." in: Molecular medicine reports, (2015) (PubMed).

Synonyms and alternative names related to Girdin

coiled-coil domain containing 88A (CCDC88A), coiled coil domain containing 88A (Ccdc88a), A430106J12Rik, AI848406, APE, Ape, C130096N06Rik, C330012F17Rik, D130005J21Rik, DKFZp459N1815, GIRDIN, Girdin, GIV, Giv, GRDN, Grdn, HkRP1, Hkrp1, KIAA1212, RGD1306694

Protein level used designations for Girdin

  • AKT-phosphorylation enhancer
  • Hook-related protein 1
  • g alpha-interacting vesicle-associated protein
  • girders of actin filament
  • girders of actin filaments
  • girdin
  • Akt-phosphorylation enhancer
  • coiled-coil domain-containing protein 88A
  • coiled-coil domain containing 88A
  • Galpha-interacting vesicle-associated protein
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