GGA1 产品
(Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1))
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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured GGA1 Categories
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Recommended GGA1 ELISA试剂盒
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Recommended GGA1 蛋白
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Latest Publications for our GGA1 Products
: "GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 39, pp. 9913-22, (2006) (PubMed).: "Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport." in: Nature structural biology, Vol. 10, Issue 5, pp. 386-93, (2003) (PubMed).
: "Crystal structure of the human GGA1 GAT domain." in: Biochemistry, Vol. 42, Issue 21, pp. 6392-9, (2003) (PubMed).
: "The interaction of the human GGA1 GAT domain with rabaptin-5 is mediated by residues on its three-helix bundle." in: Biochemistry, Vol. 42, Issue 47, pp. 13901-8, (2003) (PubMed).
Synonyms and alternative names related to GGA1
putative golgi associated, gamma adaptin ear containing,arf binding protein 1 (gga1) (Smp_164030), golgi associated, gamma adaptin ear containing, ARF binding protein 1 (Gga1), golgi-associated, gamma adaptin ear containing, ARF binding protein 1 (gga1), golgi associated, gamma adaptin ear containing, ARF binding protein 1 (GGA1), 4930406E12Rik, AU016030, AW209092, fb33h10, im:6912200, wu:fb33h10, zgc:101044Protein level used designations for GGA1
- golgi associated gamma adaptin ear containing arf binding protein 1 (gga1)
- ADP-ribosylation factor-binding protein GGA1
- gamma-adaptin-related protein 1
- golgi-localized, gamma ear-containing, ARF-binding protein 1
- ADP-ribosylation factor binding protein 1
- gamma-adaptin related protein 1
- golgi associated, gamma adaptin ear containing, ARF binding protein 1
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