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GFI1 抗体

(Growth Factor Independent 1 (GFI1))
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
GFI1 抗体  (AA 1-91) GFI1 抗体  (AA 1-91) GFI1 抗体 (AA 1-91) (ABIN561035)

GFI1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3G8 unconjugated

GFI1 抗体 GFI1 抗体 GFI1 抗体 (ABIN7245050)

GFI1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

GFI1 抗体 GFI1 抗体 GFI1 抗体 (ABIN969174)

GFI1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D7 unconjugated

GFI1 抗体 by 适用

Find GFI1 抗体 for a variety of species such as anti-Human GFI1, anti-Rat GFI1, anti-Mouse GFI1. The species listed below are among those available. Click on a link to go to the corresponding products.

GFI1 抗体 by 应用范围

Find GFI1 抗体 validated for a specific application such as WB, ELISA, IHC (p), IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

GFI1 抗体 by 抗体来源

Find GFI1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

GFI1 抗体 by 抗原表位

Find GFI1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

GFI1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal GFI1 抗体. Click on a link to go to the corresponding products.

GFI1 抗体 by 克隆

Find GFI1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

GFI1 抗体 by 标记

Find GFI1 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular GFI1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (5)
Cat. No. ABIN561035
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7245050
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN969174
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN561034
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1327463
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6971682
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6736088
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6735896
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Cow, Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN960185
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2777468
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat, Xenopus laevis
Application WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN1714623
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
Cat. No. ABIN7094713
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2603632
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
Cat. No. ABIN2621288
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN2779720
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our GFI1 抗体

Duran Alonso, Lopez Hernandez, de la Fuente, Garcia-Sancho, Giraldez, Schimmang: "Transcription factor induced conversion of human fibroblasts towards the hair cell lineage." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200210, (2019) (PubMed).

Vadnais, Chen, Fraszczak, Yu, Boulais, Pinder, Frank, Khandanpour, Hébert, Dellaire, Côté, Richard, Orthwein, Drobetsky, Möröy: "GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1." in: Nature communications, Vol. 9, Issue 1, pp. 1418, (2018) (PubMed).

Olsson, Venkatasubramanian, Chaudhri, Aronow, Salomonis, Singh, Grimes: "Single-cell analysis of mixed-lineage states leading to a binary cell fate choice." in: Nature, Vol. 537, Issue 7622, pp. 698-702, (2017) (PubMed).

Fraszczak, Helness, Chen, Vadnais, Robert, Khandanpour, Möröy: "Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1." in: PLoS ONE, Vol. 11, Issue 7, pp. e0160344, (2017) (PubMed).

Dwivedi, Anderson, Tilley, May, Morris: "Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells." in: The Journal of steroid biochemistry and molecular biology, Vol. 103, Issue 3-5, pp. 742-6, (2007) (PubMed).

Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).

Aliases for GFI1 抗体

growth factor independent 1 (Gfi1) 抗体
growth factor independent 1 transcriptional repressor (GFI1) 抗体
growth factor independent 1 transcriptional repressor (Gfi1) 抗体
AW495828 抗体
Gfi-1 抗体
GFI-1 抗体
GFI1 抗体
GFI1A 抗体
Pal-1 抗体
Pal1 抗体
SCN2 抗体
ZNF163 抗体
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