GEMIN5 产品
(Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
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This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
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Featured GEMIN5 Categories
Recommended GEMIN5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7267367
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, ELISA, IHC, IF
Validations
Cat. No.
ABIN7114527
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
Cat. No.
ABIN7451795
Quantity
20 μg
Datasheet
Datasheet
Recommended GEMIN5 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229868
Quantity
96 tests
Datasheet
Datasheet
Recommended GEMIN5 蛋白
Latest Publications for our GEMIN5 Products
: "Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors." in: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1861, Issue 2, pp. 147-157, (2018) (PubMed).: "The landscape of the non-canonical RNA-binding site of Gemin5 unveils a feedback loop counteracting the negative effect on translation." in: Nucleic acids research, Vol. 46, Issue 14, pp. 7339-7353, (2018) (PubMed).
: "The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation." in: Nucleic acids research, Vol. 44, Issue 17, pp. 8335-51, (2016) (PubMed).
: "Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5742-54, (2014) (PubMed).
: "Gemin5 promotes IRES interaction and translation control through its C-terminal region." in: Nucleic acids research, Vol. 41, Issue 2, pp. 1017-28, (2013) (PubMed).
: "Gemin5 proteolysis reveals a novel motif to identify L protease targets." in: Nucleic acids research, Vol. 40, Issue 11, pp. 4942-53, (2012) (PubMed).
: "Hepatitis C virus infection alters P-body composition but is independent of P-body granules." in: Journal of virology, Vol. 86, Issue 16, pp. 8740-9, (2012) (PubMed).
Synonyms and alternative names related to GEMIN5
gem nuclear organelle associated protein 5 (GEMIN5), gem nuclear organelle associated protein 5 (Gemin5), gem (nuclear organelle) associated protein 5 (Gemin5), AA407055, AA407208, AI451603, BB194447, C330013N08, GEMIN-5Protein level used designations for GEMIN5
- gem-associated protein 5
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