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GDNF 产品

(Glial Cell Line Derived Neurotrophic Factor (GDNF))

Categories

This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010].

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Featured GDNF Categories

GDNF 抗体

High quality antibodies with extensive validation data.

GDNF ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GDNF 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GDNF 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Human, Mouse, Rabbit, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (5)
  • (1)
Cat. No. ABIN736536
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IP, FACS
Validations
  • (5)
Cat. No. ABIN7127513
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ICC, IHC (p)
Validations
  • (4)
  • (4)
Cat. No. ABIN3044406
Quantity 100 μg
Datasheet Datasheet

Recommended GDNF ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6956098
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963049
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956096
Quantity 96 tests
Datasheet Datasheet

Recommended GDNF 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN7274722
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123092
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354986
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GDNF Products

Chen, Zhang, Chang, Yang, Wang, Fu, Wei, Chen, Tan, Huang, Sun, Ni, Yang, Wang: "A bioenergetic shift is required for spermatogonial differentiation." in: Cell discovery, Vol. 6, pp. 56, (2020) (PubMed).

Yang, Chen, Ma, Ouyang, Fang, Wei: "Co-overexpression of VEGF and GDNF in adipose-derived stem cells optimizes therapeutic effect in neurogenic erectile dysfunction model." in: Cell proliferation, Vol. 53, Issue 2, pp. e12756, (2020) (PubMed).

Guo, Lin, Xue, An, Zhang, Zhang, He, Wang, Li, Ding: "Effects of 220 MHz Pulsed Modulated Radiofrequency Field on the Sperm Quality in Rats." in: International journal of environmental research and public health, Vol. 16, Issue 7, (2019) (PubMed).

Kim, Bae, Jun, Jeon, Koo, Kim: "Acupuncture alters pro-inflammatory cytokines in the plasma of maternally separated rat pups." in: Chinese journal of integrative medicine, Vol. 23, Issue 12, pp. 943-947, (2018) (PubMed).

Niu, Li, Wu, Wu, Yan, Shang, Bai, Li, Hua: "Melatonin promotes goat spermatogonia stem cells (SSCs) proliferation by stimulating glial cell line-derived neurotrophic factor (GDNF) production in Sertoli cells." in: Oncotarget, Vol. 7, Issue 47, pp. 77532-77542, (2018) (PubMed).

Duan, Lu, Wang, Zhang, Mao, Cao, Lin, Zhang, Shuai, Shen: "The long-term fate of mesenchymal stem cells labeled with magnetic resonance imaging-visible polymersomes in cerebral ischemia." in: International journal of nanomedicine, Vol. 12, pp. 6705-6719, (2018) (PubMed).

Sun, Zhu, Yin, Guo, Xu, Xiao, Jiang, Guo, Meng, Lu, Wang, Peng: "Differentiation of adipose-derived stem cells into Schwann cell-like cells through intermittent induction: potential advantage of cellular transient memory function." in: Stem cell research & therapy, Vol. 9, Issue 1, pp. 133, (2018) (PubMed).

A, Xu, Zhao, Li, Qi, Li, Wang, Zhou: "Surface functionalization of TiO2 nanotubes with minocycline and its in vitro biological effects on Schwann cells." in: Biomedical engineering online, Vol. 17, Issue 1, pp. 88, (2018) (PubMed).

Faroni, Smith, Lu, Reid: "Human Schwann-like cells derived from adipose-derived mesenchymal stem cells rapidly de-differentiate in the absence of stimulating medium." in: The European journal of neuroscience, Vol. 43, Issue 3, pp. 417-30, (2016) (PubMed).

Yang, Liu, Chen, An, Zhang, Zhang, Zhao, He, Hao: "Efficient Generation of Functionally Active Spinal Cord Neurons from Spermatogonial Stem Cells." in: Molecular neurobiology, Vol. 54, Issue 1, pp. 788-803, (2016) (PubMed).

Synonyms and alternative names related to GDNF

glial cell derived neurotrophic factor (Gdnf), glial cell derived neurotrophic factor a (gdnfa), glial cell derived neurotrophic factor (GDNF), glial cell line derived neurotrophic factor (Gdnf), glial cell derived neurotrophic factor L homeolog (gdnf.L), AI385739, ATF1, ATF2, gdnf, GDNF, gdnfa, hfb1-gdnf, HFB1-GDNF, HSCR3

Protein level used designations for GDNF

  • ATF
  • Glial cell line derived neutrophic factor
  • astrocyte-derived trophic factor
  • glial cell line derived neurotrophic factor
  • glial cell line-derived neurotrophic factor
  • zGDNF
  • glial cell line-derived neurotrophic factor long form
  • glial cell derived neurotrophic factor
  • glial cell-line derived neurotrophic factor
  • mGDNF
  • neurotrophic factor
  • glial cell line-derived neurotrophic factor a
  • xGDNF
  • glia-derived neurotrophic growth factor
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