GCS1 产品
(Mannosyl-Oligosaccharide Glucosidase (MOGS))
Categories
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
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Featured GCS1 Categories
Recommended GCS1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN7256322
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6740983
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6143945
Quantity
100 μL
Datasheet
Datasheet
Recommended GCS1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419994
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419997
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3114747
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GCS1 Products
: "p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 7, pp. 3892-3902, (2019) (PubMed).: "Processing of N-linked carbohydrate chains in a patient with glucosidase I deficiency (CDG type IIb)." in: Glycobiology, Vol. 12, Issue 8, pp. 473-83, (2002) (PubMed).
: "A novel disorder caused by defective biosynthesis of N-linked oligosaccharides due to glucosidase I deficiency." in: American journal of human genetics, Vol. 66, Issue 6, pp. 1744-56, (2001) (PubMed).
Synonyms and alternative names related to GCS1
mannosyl-oligosaccharide glucosidase (AFUA_6G04210), mannosyl-oligosaccharide glucosidase (Tc00.1047053511015.10), mannosyl-oligosaccharide glucosidase (Tc00.1047053511805.10), mannosyl-oligosaccharide glucosidase GCS1 (LOC5576381), mannosyl-oligosaccharide glucosidase (AOR_1_260114), mannosyl-oligosaccharide glucosidase (MGYG_00305), mannosyl-oligosaccharide glucosidase (TERG_01248), mannosyl-oligosaccharide glucosidase L homeolog (mogs.L), mannosyl oligosaccharide glucosidase (TTHERM_00636930), mannosyl oligosaccharide glucosidase (LOAG_03690), glucosidase 1 (Gcs1), mannosyl-oligosaccharide glucosidase (MOGS), mannosyl-oligosaccharide glucosidase (Mogs), mannosyl-oligosaccharide glucosidase (mogs), 1810017N02Rik, Afu6g04210, AI181835, AO090701000141, CDG2B, CWH41, DER7, GCS1, Gcs1, gcs1, im:7160827, Mogs, wu:fe50a12, wu:fk09a10, zgc:158312Protein level used designations for GCS1
- mannosyl-oligosaccharide glucosidase
- Mannosyl oligosaccharide glucosidase
- mannosyl oligosaccharide glucosidase
- glycoprotein-processing glucosidase I
- glucosidase I
- processing A-glucosidase I
- glucosidase 1
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