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GCLM 抗体

(Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008].
GCLM 抗体  (AA 40-251) GCLM 抗体  (AA 40-251) GCLM 抗体 (AA 40-251) (ABIN7433051)

GCLM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

GCLM 抗体  (C-Term) GCLM 抗体  (C-Term) GCLM 抗体 (C-Term) (ABIN653046)

GCLM 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22980 unconjugated

GCLM 抗体  (Regulatory Subunit) GCLM 抗体  (Regulatory Subunit) GCLM 抗体 (Regulatory Subunit) (ABIN7154002)

GCLM 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

GCLM 抗体 by Grade

Find GCLM 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

GCLM 抗体 by 适用

Find GCLM 抗体 for a variety of species such as anti-Human GCLM, anti-Mouse GCLM, anti-Rat GCLM. The species listed below are among those available. Click on a link to go to the corresponding products.

GCLM 抗体 by 应用范围

Find GCLM 抗体 validated for a specific application such as WB, IHC, ELISA, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

GCLM 抗体 by 抗体来源

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GCLM 抗体 by 抗原表位

Find GCLM 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

GCLM 抗体 by 克隆形成能力

Find available monoclonal or polyclonal GCLM 抗体. Click on a link to go to the corresponding products.

GCLM 抗体 by 克隆

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GCLM 抗体 by 标记

Find GCLM 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular GCLM 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (11)
Cat. No. ABIN7433051
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, FACS, IHC (p)
Validations
  • (1)
  • (7)
Cat. No. ABIN653046
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (4)
Cat. No. ABIN7154002
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
  • (3)
Cat. No. ABIN516058
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS, IHC (p), EIA
Validations
  • (5)
Cat. No. ABIN952478
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN516055
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Pig, Rat
Application WB, IHC, ELISA
Validations
  • (2)
  • (2)
Cat. No. ABIN6261915
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN516056
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6747158
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC
Validations
  • (1)
Cat. No. ABIN7257549
Quantity 200 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (2)
  • (1)
Cat. No. ABIN2785805
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IHC (p), IF (p), IF (cc)
Validations
Cat. No. ABIN6943524
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7154003
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7154004
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7154005
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GCLM 抗体

Cao, Poddar, Magtanong, Lumb, Mileur, Reid, Dovey, Wang, Locasale, Stone, Cole, Carette, Dixon: "A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity." in: Cell reports, Vol. 26, Issue 6, pp. 1544-1556.e8, (2019) (PubMed).

Zou, Wang, Peng, Wei: "Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5987183, (2017) (PubMed).

Li, Sun, Liu, Zhao, Shao: "Silymarin protects against acrylamide-induced neurotoxicity via Nrf2 signalling in PC12 cells." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 102, pp. 93-101, (2017) (PubMed).

Lu, Samanta, Xiang, Zhang, Hu, Chen, Bullen, Semenza: "Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 33, pp. E4600-9, (2015) (PubMed).

Tomasi, Ryoo, Yang, Iglesias Ara, Ko, Lu: "Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice." in: Free radical biology & medicine, Vol. 68, pp. 148-58, (2014) (PubMed).

Chen, Jiang, Hu, Zhang: "The protective role of resveratrol in the sodium arsenite-induced oxidative damage via modulation of intracellular GSH homeostasis." in: Biological trace element research, Vol. 155, Issue 1, pp. 119-31, (2014) (PubMed).

Ramani, Tomasi, Yang, Ko, Lu: "Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis." in: The Journal of biological chemistry, Vol. 287, Issue 43, pp. 36341-55, (2012) (PubMed).

Sharon, Mor, Golan-lev, Fainsod, Benvenisty: "Molecular and functional characterizations of gastrula organizer cells derived from human embryonic stem cells." in: Stem cells (Dayton, Ohio), Vol. 29, Issue 4, pp. 600-8, (2011) (PubMed).

Abel, Bubel, Simper, Powell, McClellan, Andreeff, MacLeod, DiGiovanni: "Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway." in: Toxicology and applied pharmacology, Vol. 255, Issue 2, pp. 176-83, (2011) (PubMed).

Hardwick, Fisher, Canet, Lake, Cherrington: "Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 38, Issue 12, pp. 2293-301, (2010) (PubMed).

Aliases for GCLM 抗体

glutamate-cysteine ligase regulatory subunit (PTRG_09814) 抗体
glutamate cysteine ligase, modifier subunit (Gclm) 抗体
glutamate-cysteine ligase modifier subunit (GCLM) 抗体
glutamate-cysteine ligase, modifier subunit (gclm) 抗体
glutamate-cysteine ligase, modifier subunit L homeolog (gclm.L) 抗体
glutamate-cysteine ligase, modifier subunit (Gclm) 抗体
glutamate-cysteine ligase modifier subunit (Gclm) 抗体
AI649393 抗体
Gcmc 抗体
Glclr 抗体
GLCLR 抗体
id:ibd3182 抗体
wu:fi24c07 抗体
zgc:55903 抗体
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