GCLC 抗体
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010].
recommended
recommended
GCLC 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 兔, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
recommended
GCLC 抗体 by 应用范围
Find GCLC 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
GCLC 抗体 by 抗体来源
Find GCLC 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
GCLC 抗体 by 克隆形成能力
Find available monoclonal or polyclonal GCLC 抗体. Click on a link to go to the corresponding products.
GCLC 抗体 by 克隆
Find GCLC 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
GCLC 抗体 by 标记
Find GCLC 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular GCLC 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (6)
- (7)
Cat. No.
ABIN561050
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (5)
Cat. No.
ABIN2774078
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, FACS
Validations
- (7)
Cat. No.
ABIN3031076
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse, Pig, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (2)
- (3)
Cat. No.
ABIN6261919
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
- (2)
- (4)
Cat. No.
ABIN3042420
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, FACS, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN655884
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (2)
Cat. No.
ABIN6141016
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC
Validations
- (4)
Cat. No.
ABIN1858972
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (2)
- (3)
Cat. No.
ABIN2785780
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, FACS, IHC (p), EIA
Validations
- (4)
Cat. No.
ABIN952477
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7435583
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7252117
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6747154
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN3031077
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (1)
Cat. No.
ABIN7153998
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GCLC 抗体
: "Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks." in: Biological trace element research, Vol. 186, Issue 1, pp. 226-237, (2018) (PubMed).: "Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice." in: PLoS ONE, Vol. 13, Issue 5, pp. e0198139, (2018) (PubMed).
: "Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5987183, (2017) (PubMed).
: "Silymarin protects against acrylamide-induced neurotoxicity via Nrf2 signalling in PC12 cells." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 102, pp. 93-101, (2017) (PubMed).
: "Bone marrow mesenchymal stem cells protect against bleomycin-induced pulmonary fibrosis in rat by activating Nrf2 signaling." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7752-61, (2016) (PubMed).
: "Electroacupuncture alleviates cerebral ischemia and reperfusion injury via modulation of the ERK1/2 signaling pathway." in: Neural regeneration research, Vol. 11, Issue 7, pp. 1090-8, (2016) (PubMed).
: "Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus." in: PLoS ONE, Vol. 9, Issue 4, pp. e94460, (2014) (PubMed).
: "Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 9, pp. 710-22, (2014) (PubMed).
: "The role of glutathione in mercury tolerance resembles its function under cadmium stress in Arabidopsis." in: Metallomics : integrated biometal science, Vol. 6, Issue 2, pp. 356-66, (2014) (PubMed).
: "Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice." in: Free radical biology & medicine, Vol. 68, pp. 148-58, (2014) (PubMed).
Aliases for GCLC 抗体
glutamate-cysteine ligase catalytic subunit (GCLC) 抗体glutamate-cysteine ligase, catalytic subunit (gclc) 抗体
Glutamate-cysteine ligase catalytic subunit (Gclc) 抗体
gamma glutamylcysteine synthetase (LbGCS) 抗体
gamma glutamylcysteine synthetase (gcsA) 抗体
glutamate-cysteine ligase, catalytic subunit L homeolog (gclc.L) 抗体
glutamate-cysteine ligase, catalytic subunit S homeolog (gclc.S) 抗体
gamma-glutamylcysteine synthetase (GSH1) 抗体
glutamate-cysteine ligase, catalytic subunit (Gclc) 抗体
glutamate-cysteine ligase catalytic subunit (Gclc) 抗体
2259 抗体
cb1049 抗体
CG2259 抗体
D9Wsu168e 抗体
DDBDRAFT_0186120 抗体
DDBDRAFT_0231403 抗体
DDB_0186120 抗体
DDB_0231403 抗体
Dmel\\CG2259 抗体
DmGCLC 抗体
DmGCS 抗体
DmGCSh 抗体
fe36e11 抗体
GCL 抗体
GCLC 抗体
gclc 抗体
GCLc 抗体
Gcs 抗体
GCS 抗体
GCSh 抗体
Gcsh 抗体
Ggcs-hs 抗体
GLCL 抗体
GLCL-H 抗体
GLCLC 抗体
Glclc 抗体
MGC146287 抗体
wu:fe36e11 抗体
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