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G3BP1 产品

(GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

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This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].

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Featured G3BP1 Categories

G3BP1 抗体

High quality antibodies with extensive validation data.

G3BP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

G3BP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended G3BP1 抗体

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Reactivity
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Cat. No.
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Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), RNAi
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  • (7)
Cat. No. ABIN564390
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
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  • (4)
Cat. No. ABIN523522
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC, IP
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  • (6)
Cat. No. ABIN2780222
Quantity 100 μL
Datasheet Datasheet

Recommended G3BP1 ELISA试剂盒

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Reactivity Cow
Analytical Method
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Cat. No. ABIN1154507
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380586
Quantity 2 x 96 tests
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Recommended G3BP1 蛋白

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Cat. No. ABIN7123226
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1354601
Quantity 10 μg
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Source Wheat germ
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Cat. No. ABIN1354599
Quantity 10 μg
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Latest Publications for our G3BP1 Products

Hu, Wang, Tang, Yang, Qin, Chen: "Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs." in: PLoS pathogens, Vol. 14, Issue 3, pp. e1006948, (2018) (PubMed).

Ye, Pan, Wang, Fang, Ma, Zhu, Shi, Zhang, Zheng, Chen, Li, Xiao: "Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms." in: Frontiers in immunology, Vol. 9, pp. 1142, (2018) (PubMed).

Martin, Bellora, González-Vallinas, Irimia, Chebli, de Toledo, Raabe, Eyras, Urlaub, Blencowe, Tazi: "Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum." in: Journal of neurochemistry, Vol. 139, Issue 3, pp. 349-368, (2016) (PubMed).

Lind, Svedin, Domsgen, Kapell, Laitinen, Moll, Flodström-Tullberg: "Coxsackievirus counters the host innate immune response by blocking type III interferon expression." in: The Journal of general virology, Vol. 97, Issue 6, pp. 1-12, (2016) (PubMed).

Schulte, Liu, Panas, Thaa, Dickson, Götte, Achour, McInerney: "Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication." in: Open biology, Vol. 6, Issue 7, (2016) (PubMed).

He, Yang, Abdellatif, Sayed: "GTPase Activating Protein (Sh3 Domain) Binding Protein 1 Regulates the Processing of MicroRNA-1 during Cardiac Hypertrophy." in: PLoS ONE, Vol. 10, Issue 12, pp. e0145112, (2015) (PubMed).

Luo, Fang, Jin, Wang, An, Xu, Chen, Xiao: "Label-free quantitative phosphoproteomic analysis reveals differentially regulated proteins and pathway in PRRSV-infected pulmonary alveolar macrophages." in: Journal of proteome research, Vol. 13, Issue 3, pp. 1270-80, (2014) (PubMed).

Kaehler, Isensee, Hucho, Lehrach, Krobitsch: "5-Fluorouracil affects assembly of stress granules based on RNA incorporation." in: Nucleic acids research, Vol. 42, Issue 10, pp. 6436-47, (2014) (PubMed).

Martin, Zekri, Metz, Maurice, Chebli, Vignes, Tazi: "Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons." in: Journal of neurochemistry, (2013) (PubMed).

Kaehler, Isensee, Nonhoff, Terrey, Hucho, Lehrach, Krobitsch: "Ataxin-2-like is a regulator of stress granules and processing bodies." in: PLoS ONE, Vol. 7, Issue 11, pp. e50134, (2012) (PubMed).

Synonyms and alternative names related to G3BP1

G3BP stress granule assembly factor 1 (G3BP1), GTPase activating protein (SH3 domain) binding protein 1 (g3bp1), GTPase activating protein (SH3 domain) binding protein 1 L homeolog (g3bp1.L), Ras-GTPase-activating protein SH3-domain-binding protein (LOC100304885), G3BP stress granule assembly factor 1 (G3bp1), GTPase activating protein (SH3 domain) binding protein 1 (G3bp1), AI849976, B430204O07, C87777, fj17h05, G3BP, g3bp, G3bp, G3BP1, HDH-VIII, MGC53271, mKIAA4115, RGD1310666, wu:fj17h05, zgc:56034

Protein level used designations for G3BP1

  • ATP-dependent DNA helicase VIII
  • G3BP-1
  • GAP SH3 domain-binding protein 1
  • GAP binding protein
  • Ras-GTPase-activating protein SH3-domain-binding protein
  • RasGAP-associated endoribonuclease G3BP
  • ras GTPase-activating protein-binding protein 1
  • GTPase activating protein (SH3 domain) binding protein 1
  • ATP-dependent DNA/RNA helicase G3BP
  • Ras-GTPase-activating protein SH3-domain binding protein 1
  • GAP SH3 binding protein
  • HDH-VIII
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