GAD 抗体
(Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008].
recommended
recommended
GAD1 适用: 人 WB, IHC, ICC, IHC (p), IF, IHC (fro), IHC (ff), IHC (wm) 宿主: 兔 Polyclonal unconjugated
recommended
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Application
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Quantity
100 μL
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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WB, IHC, ELISA, ICC, IF
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Application
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
ABIN7153952
Quantity
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Datasheet
Datasheet
Reactivity
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Application
IHC
Validations
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Cat. No.
ABIN7456062
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IHC
Validations
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Cat. No.
ABIN7456014
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Latest Publications for our GAD 抗体
: "A novel homozygous mutation in GAD1 gene described in a schizophrenic patient impairs activity and dimerization of GAD67 enzyme." in: Scientific reports, Vol. 8, Issue 1, pp. 15470, (2018) (PubMed).: "Dietary Restriction Affects Neuronal Response Property and GABA Synthesis in the Primary Visual Cortex." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149004, (2016) (PubMed).
: "Accelerated intoxication of GABAergic synapses by botulinum neurotoxin A disinhibits stem cell-derived neuron networks prior to network silencing." in: Frontiers in cellular neuroscience, Vol. 9, pp. 159, (2015) (PubMed).
: "Characterization of continuous B-cell epitopes in the N-terminus of glutamate decarboxylase67 using monoclonal antibodies." in: Journal of peptide science : an official publication of the European Peptide Society, Vol. 20, Issue 12, pp. 928-34, (2014) (PubMed).
: "Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome." in: Neurobiology of disease, Vol. 63, pp. 92-106, (2014) (PubMed).
: "Cellular distribution of the NMDA-receptor activated synapto-nuclear messenger Jacob in the rat brain." in: Brain structure & function, Vol. 219, Issue 3, pp. 843-60, (2014) (PubMed).
: "Interaction of NAP-22 with brain glutamic acid decarboxylase (GAD)." in: Neuroscience letters, Vol. 537, pp. 50-4, (2013) (PubMed).
: "High-fat diets induce changes in hippocampal glutamate metabolism and neurotransmission." in: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 4, pp. E396-402, (2012) (PubMed).
: "Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice." in: Neuroscience, Vol. 189, pp. 108-22, (2011) (PubMed).
: "Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium." in: Respiratory research, Vol. 11, pp. 150, (2010) (PubMed).
Aliases for GAD 抗体
glutamate decarboxylase 1 (GAD1) 抗体glutamate decarboxylase 1 L homeolog (gad1.1.L) 抗体
glutamate decarboxylase (GAD) 抗体
glutamate decarboxylase 1 (Gad1) 抗体
glutamate decarboxylase 1b (gad1b) 抗体
CPSQ1 抗体
cpsq1 抗体
EP10 抗体
GAD 抗体
Gad-1 抗体
GAD-67 抗体
gad1 抗体
GAD1 抗体
gad1-A 抗体
GAD25 抗体
GAD44 抗体
gad67 抗体
GAD67 抗体
Gad67 抗体
GLUTAMATE DECARBOXYLASE 抗体
glutamate decarboxylase 抗体
GLUTAMATE DECARBOXYLASE 1 抗体
MKP11.30 抗体
MKP11_30 抗体
SCP 抗体
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