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GABRD 产品

(GABA A Receptor delta (GABRD))

Categories

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

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Featured GABRD Categories

GABRD 抗体

High quality antibodies with extensive validation data.

GABRD 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GABRD 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Human, Mouse, Rabbit
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN2792262
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6257709
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6735767
Quantity 100 μL
Datasheet Datasheet

Recommended GABRD ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6209852
Quantity 96 tests
Datasheet Datasheet

Recommended GABRD 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422715
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422712
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GABRD Products

Popoola, Cameron: "Maternal care-related differences in males and females rats' sensitivity to ethanol and the associations between the GABAergic system and steroids in males." in: Developmental psychobiology, Vol. 60, Issue 4, pp. 380-394, (2018) (PubMed).

Chen, Li, Zhang, Hu, Li, Feng, Yao, Zhang, Wan, Zhang et al.: "Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A ..." in: The journal of pain : official journal of the American Pain Society, (2018) (PubMed).

Popoola, Nizhnikov, Cameron: "Strain-specific programming of prenatal ethanol exposure across generations." in: Alcohol (Fayetteville, N.Y.), Vol. 60, pp. 191-199, (2017) (PubMed).

Borrow, Cameron: "Maternal care and affective behavior in female offspring: Implication of the neurosteroid/GABAergic system." in: Psychoneuroendocrinology, Vol. 76, pp. 29-37, (2016) (PubMed).

Chugh, Ali, Bakochi, Bahonjic, Etholm, Ekdahl: "Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132366, (2015) (PubMed).

Centanni, Teppen, Risher, Fleming, Moss, Acheson, Mulholland, Pandey, Chandler, Swartzwelder: "Adolescent alcohol exposure alters GABAA receptor subunit expression in adult hippocampus." in: Alcoholism, clinical and experimental research, Vol. 38, Issue 11, pp. 2800-8, (2014) (PubMed).

Diaz, Vollmer, Zamudio-Bulcock, Vollmer, Blomquist, Morton, Everett, Zurek, Yu, Orser, Valenzuela: "Repeated intermittent alcohol exposure during the third trimester-equivalent increases expression of the GABA(A) receptor δ subunit in cerebellar granule neurons and delays motor development in rats." in: Neuropharmacology, Vol. 79, pp. 262-74, (2014) (PubMed).

Lee, Sarkar, Maguire: "Loss of Gabrd in CRH neurons blunts the corticosterone response to stress and diminishes stress-related behaviors." in: Psychoneuroendocrinology, Vol. 41, pp. 75-88, (2014) (PubMed).

Ma, Yao, Fu, Yu: "Development of layer 1 neurons in the mouse neocortex." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 24, Issue 10, pp. 2604-18, (2014) (PubMed).

Carlson, OBuckley, Thomas, Thiele, Morrow: "Altered GABAA receptor expression and seizure threshold following acute ethanol challenge in mice lacking the RIIβ subunit of PKA." in: Neurochemical research, Vol. 39, Issue 6, pp. 1079-87, (2014) (PubMed).

Synonyms and alternative names related to GABRD

gamma-aminobutyric acid type A receptor delta subunit (GABRD), gamma-aminobutyric acid type A receptor delta subunit (Gabrd), gamma-aminobutyric acid (GABA) A receptor, subunit delta (Gabrd), AI853201, EIG10, EJM7, GABAA-RD, GABRD, GEFSP5

Protein level used designations for GABRD

  • gamma-aminobutyric acid (GABA) A receptor, delta
  • gamma-aminobutyric acid receptor subunit delta-like
  • GABA(A) receptor subunit delta
  • GABA(A) receptor, delta
  • GABA-A receptor, delta polypeptide
  • gamma-aminobutyric acid receptor subunit delta
  • GABA-A receptor delta-subunit
  • GABAA receptor delta subunit
  • gamma-aminobutyric acid A receptor, delta
  • gamma-aminobutyric acid (GABA-A) receptor, subunit delta
  • gamma-aminobutyric acid A receptor, delta
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